Wednesday, November 14, 2018 | Pre-Meeting Workshop – Half Day
1:00 pm – 3:30 pm
METHODS IN LIPID OXIDATION
Chairs: Henry Jay Forman, PhD, University of Southern California; University of California, Merced, USA; Corinne Spickett, MA, DPhil, Aston University, Birmingham, UK
Description:
Lipid oxidation generates numerous bioactive products, which can act as either signaling molecules involved in cell growth regulation, and stimulants of increased antioxidant defense, or signal for and participate in cell death. Hence, various acute and chronic human diseases metabolic, degenerative, inflammatory and malignant are associated with lipid oxidation. Therefore, this workshop will give an updated overview on methods in lipid oxidation research that might clarify the most relevant aspects of lipid oxidation and support its positioning within the interdisciplinarity of free radical biology and medicine.
13:00 – 13:10 Welcome
13:10 – 13:40 MS-based identification of covalent adducts in oxidize LDL
Koji Uchida, Ph.D., The University of Tokyo, Japan
13:40 – 14:10 Methods to measure isolevuglandin protein and phospholipid adducts
Sean Davies, Ph.D., Vanderbilt University, Nashville, USA
14:10 – 14:25 Break
14:25 – 14:55 Immunochemical findings of HNE-His adducts in human diseases
Neven Zarkovic, M.D.,Ph.D., LabOS, Rudjer Boskovic Institute, Zagreb, Croatia
14:55 – 15:25 Nitro-fatty acids: detection, electrophilic signaling and therapeutics
Homero Rubbo, Ph.D., Universidad de la Republica, Montevideo, Uruguay
SFRBM Pre-Meeting Workshop
Wednesday, November 14, 2018 | Pre-Meeting Workshop – Half Day
1:00 pm – 3:30 pm
METHODS IN LIPID OXIDATION
Chairs: Henry Jay Forman, PhD, University of Southern California; University of California, Merced, USA; Corinne Spickett, MA, DPhil, Aston University, Birmingham, UK
Description:
Lipid oxidation generates numerous bioactive products, which can act as either signaling molecules involved in cell growth regulation, and stimulants of increased antioxidant defense, or signal for and participate in cell death. Hence, various acute and chronic human diseases metabolic, degenerative, inflammatory and malignant are associated with lipid oxidation. Therefore, this workshop will give an updated overview on methods in lipid oxidation research that might clarify the most relevant aspects of lipid oxidation and support its positioning within the interdisciplinarity of free radical biology and medicine.
13:00 – 13:10 Welcome
13:10 – 13:40 MS-based identification of covalent adducts in oxidize LDL
Koji Uchida, Ph.D., The University of Tokyo, Japan
13:40 – 14:10 Methods to measure isolevuglandin protein and phospholipid adducts
Sean Davies, Ph.D., Vanderbilt University, Nashville, USA
14:10 – 14:25 Break
14:25 – 14:55 Immunochemical findings of HNE-His adducts in human diseases
Neven Zarkovic, M.D.,Ph.D., LabOS, Rudjer Boskovic Institute, Zagreb, Croatia
14:55 – 15:25 Nitro-fatty acids: detection, electrophilic signaling and therapeutics
Homero Rubbo, Ph.D., Universidad de la Republica, Montevideo, Uruguay
15:25 – 15:30 Summary