{"id":466,"date":"2019-06-14T10:59:50","date_gmt":"2019-06-14T08:59:50","guid":{"rendered":"https:\/\/sites.unimi.it\/apisgroup\/?p=466"},"modified":"2022-01-21T13:09:27","modified_gmt":"2022-01-21T12:09:27","slug":"bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides","status":"publish","type":"post","link":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/","title":{"rendered":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"> <\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignleft\"><img decoding=\"async\" src=\"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/pirrolidfront.jpg\" alt=\"\"\/><\/figure><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"> amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While \u03b1,\u03b1-disubstituted and \u03b2-amino acids are widely studied, \u03b3-derivatives have been less exploited. Here we report the conformational study on the bicyclic unnatural \u03b3 amino acid, 4,5,6,6a-tetrahydro-3a<em>H<\/em>-pyrrolo[3,4-d]isoxazole-3-carboxylic acid&nbsp;<strong>1<\/strong>. In model peptides, the (+)-(3a<em>R<\/em>6a<em>S<\/em>)-enantiomer is able to stabilize \u03b1-turn conformation when associated to glycine, as showed by&nbsp;<sup>1<\/sup>H-NMR, FT-IR, and circular dichroism experiments, and molecular modeling studies. \u03b1-turn is a structural motif occurring in many biologically active protein sites, although its stabilization on isolated peptides is quite uncommon. Our results make the unnatural \u03b3-amino acid&nbsp;<strong>1<\/strong>&nbsp;of particular interest for the development of bioactive peptidomimetics. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fchem.2019.00133\/full\">doi.org\/10.3389\/fchem.2019.00133<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While \u03b1,\u03b1-disubstituted and \u03b2-amino acids are widely studied, \u03b3-derivatives have been less exploited. Here we report the conformational study on the&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":547,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,5,7],"tags":[],"class_list":["post-466","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-application","category-peptidomimetics","category-amino-acid"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group\" \/>\n<meta property=\"og:description\" content=\"amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While \u03b1,\u03b1-disubstituted and \u03b2-amino acids are widely studied, \u03b3-derivatives have been less exploited. Here we report the conformational study on the&#046;&#046;&#046;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-\u03b3-amino-acid-a-constrained-scaffold-for-stabilizing-\u03b1-turn-conformation-in-isolated-peptides\/\" \/>\n<meta property=\"og:site_name\" content=\"APIS group\" \/>\n<meta property=\"article:published_time\" content=\"2019-06-14T08:59:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-01-21T12:09:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"765\" \/>\n\t<meta property=\"og:image:height\" content=\"911\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"emanuela erba\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"emanuela erba\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/\"},\"author\":{\"name\":\"emanuela erba\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#\\\/schema\\\/person\\\/983a9690b88e39642466bb60ddc30c84\"},\"headline\":\"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides\",\"datePublished\":\"2019-06-14T08:59:50+00:00\",\"dateModified\":\"2022-01-21T12:09:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/\"},\"wordCount\":133,\"publisher\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/immagine-isosazolina.jpg\",\"articleSection\":[\"application\",\"Peptidomimetics\",\"unnatural amino acid\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/\",\"url\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/\",\"name\":\"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/immagine-isosazolina.jpg\",\"datePublished\":\"2019-06-14T08:59:50+00:00\",\"dateModified\":\"2022-01-21T12:09:27+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#breadcrumb\"},\"inLanguage\":\"it-IT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#primaryimage\",\"url\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/immagine-isosazolina.jpg\",\"contentUrl\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/immagine-isosazolina.jpg\",\"width\":765,\"height\":911},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/2019\\\/06\\\/14\\\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#website\",\"url\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/\",\"name\":\"APIS group\",\"description\":\"Amino acids, Peptidomimetics, peptides, protein InteractionS group\",\"publisher\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"it-IT\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#organization\",\"name\":\"unimi.it\",\"url\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2015\\\/06\\\/logouniv.jpeg\",\"contentUrl\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/wp-content\\\/uploads\\\/2015\\\/06\\\/logouniv.jpeg\",\"width\":186,\"height\":64,\"caption\":\"unimi.it\"},\"image\":{\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/sites.unimi.it\\\/apisgroup\\\/#\\\/schema\\\/person\\\/983a9690b88e39642466bb60ddc30c84\",\"name\":\"emanuela erba\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g\",\"caption\":\"emanuela erba\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group","robots":{"index":"noindex","follow":"follow"},"og_locale":"it_IT","og_type":"article","og_title":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group","og_description":"amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While \u03b1,\u03b1-disubstituted and \u03b2-amino acids are widely studied, \u03b3-derivatives have been less exploited. Here we report the conformational study on the&#46;&#46;&#46;","og_url":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-\u03b3-amino-acid-a-constrained-scaffold-for-stabilizing-\u03b1-turn-conformation-in-isolated-peptides\/","og_site_name":"APIS group","article_published_time":"2019-06-14T08:59:50+00:00","article_modified_time":"2022-01-21T12:09:27+00:00","og_image":[{"width":765,"height":911,"url":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg","type":"image\/jpeg"}],"author":"emanuela erba","twitter_card":"summary_large_image","twitter_misc":{"Scritto da":"emanuela erba","Tempo di lettura stimato":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#article","isPartOf":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/"},"author":{"name":"emanuela erba","@id":"https:\/\/sites.unimi.it\/apisgroup\/#\/schema\/person\/983a9690b88e39642466bb60ddc30c84"},"headline":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides","datePublished":"2019-06-14T08:59:50+00:00","dateModified":"2022-01-21T12:09:27+00:00","mainEntityOfPage":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/"},"wordCount":133,"publisher":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/#organization"},"image":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#primaryimage"},"thumbnailUrl":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg","articleSection":["application","Peptidomimetics","unnatural amino acid"],"inLanguage":"it-IT"},{"@type":"WebPage","@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/","url":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/","name":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides - APIS group","isPartOf":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#primaryimage"},"image":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#primaryimage"},"thumbnailUrl":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg","datePublished":"2019-06-14T08:59:50+00:00","dateModified":"2022-01-21T12:09:27+00:00","breadcrumb":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#breadcrumb"},"inLanguage":"it-IT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/"]}]},{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#primaryimage","url":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg","contentUrl":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2019\/06\/immagine-isosazolina.jpg","width":765,"height":911},{"@type":"BreadcrumbList","@id":"https:\/\/sites.unimi.it\/apisgroup\/2019\/06\/14\/bicyclic-pyrrolidine-isoxazoline-%ce%b3-amino-acid-a-constrained-scaffold-for-stabilizing-%ce%b1-turn-conformation-in-isolated-peptides\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.unimi.it\/apisgroup\/"},{"@type":"ListItem","position":2,"name":"Bicyclic Pyrrolidine-Isoxazoline \u03b3 Amino Acid: A Constrained Scaffold for Stabilizing \u03b1-Turn Conformation in Isolated Peptides"}]},{"@type":"WebSite","@id":"https:\/\/sites.unimi.it\/apisgroup\/#website","url":"https:\/\/sites.unimi.it\/apisgroup\/","name":"APIS group","description":"Amino acids, Peptidomimetics, peptides, protein InteractionS group","publisher":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.unimi.it\/apisgroup\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"it-IT"},{"@type":"Organization","@id":"https:\/\/sites.unimi.it\/apisgroup\/#organization","name":"unimi.it","url":"https:\/\/sites.unimi.it\/apisgroup\/","logo":{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/sites.unimi.it\/apisgroup\/#\/schema\/logo\/image\/","url":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2015\/06\/logouniv.jpeg","contentUrl":"https:\/\/sites.unimi.it\/apisgroup\/wp-content\/uploads\/2015\/06\/logouniv.jpeg","width":186,"height":64,"caption":"unimi.it"},"image":{"@id":"https:\/\/sites.unimi.it\/apisgroup\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/sites.unimi.it\/apisgroup\/#\/schema\/person\/983a9690b88e39642466bb60ddc30c84","name":"emanuela erba","image":{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/secure.gravatar.com\/avatar\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/1e7cde6c268a8211405dc8ae2c27c5ce7bf21dccba0902783bd783ecdacca7ee?s=96&d=mm&r=g","caption":"emanuela erba"}}]}},"_links":{"self":[{"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/posts\/466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/comments?post=466"}],"version-history":[{"count":5,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/posts\/466\/revisions"}],"predecessor-version":[{"id":484,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/posts\/466\/revisions\/484"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/media\/547"}],"wp:attachment":[{"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/media?parent=466"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/categories?post=466"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.unimi.it\/apisgroup\/wp-json\/wp\/v2\/tags?post=466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}