{"id":63,"date":"2021-09-23T11:46:17","date_gmt":"2021-09-23T11:46:17","guid":{"rendered":"https:\/\/sites.unimi.it\/bressanone\/?page_id=63"},"modified":"2026-02-10T12:09:09","modified_gmt":"2026-02-10T12:09:09","slug":"the-program","status":"publish","type":"page","link":"https:\/\/sites.unimi.it\/bressanone\/the-program\/","title":{"rendered":"The program"},"content":{"rendered":"\n

Monday 9th<\/strong><\/p>\n\n\n\n

14.15-14.30 Welcome<\/p>\n\n\n\n

14.30-15.00 Gabriella Heller (UCL, UK)<\/p>\n\n\n\n

Small-molecule binding to disordered proteins<\/em><\/p>\n\n\n\n

15.15-15.45 Gianluca Lattanzi (UniTn)<\/p>\n\n\n\n

Exploring Biological Complexity through Molecular Simulations<\/em><\/p>\n\n\n\n

16.00-16.30 Davide Mazza (U. San Raffaele, Milano)<\/p>\n\n\n\n

Probing transcription factors at single molecule level in living cells: search mechanism and non-equilibrium kinetics<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

17.00-17.30 Alessandro Angelini (UniVe)<\/p>\n\n\n\n

Synergistic evolution of macrocyclic peptide ligands: combining in vitro and in silico approaches<\/em><\/p>\n\n\n\n

17.45-18.15 short talks:<\/p>\n\n\n\n

Fabio Mazza (UniTn), Decoding the Functional Impact and Epistatic Interactions of Germline and Somatic Variants in Cancer.
<\/em>Michele Monti and Jonathan Fiorentino (IIT) Interpretability vs black boxes in protein encoding<\/em><\/p>\n\n\n\n

<\/div>\n\n\n\n

Tuesday 10th<\/strong><\/p>\n\n\n\n

9.00-9.30 Elizabeth Proctor (U. of Virginia)<\/p>\n\n\n\n

Neuroimmune response to amyloid-<\/em>\u03b2<\/em> deposition negatively impacts neural circuit activity in Alzheimer\u2019s disease<\/em><\/p>\n\n\n\n

9.45-10.15 Francesco Aprile (Imperial College, UK)<\/p>\n\n\n\n

Integrative nanobody discovery to target protein aggregates<\/em><\/p>\n\n\n\n

10.30-11.00 Giovanni Bussi (Sissa)<\/p>\n\n\n\n

A physics-based model to reconstruct RNA dynamics based on chemical probing data<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

11.30-12.00 Eli Slenders (IIT Genova)<\/p>\n\n\n\n

Fluorescence lifetime fluctuation spectroscopy for the study of biomolecular condensates<\/em><\/em><\/p>\n\n\n\n

12.15-12.45 short talks<\/em>:<\/p>\n\n\n\n

Giovanni Novi Inverardi  <\/em>(UniTn) Adsorption of silica oligomers on biomolecules: Structural and dynamical insights for atom probe tomography via classic MD simulations<\/em><\/p>\n\n\n\n

Ottavia Schulte (UniRoma1) Functional bottlenecks can emerge from non-epistatic underlying traits<\/em><\/em><\/p>\n\n\n\n

lunch break<\/em><\/p>\n\n\n\n

14.30-15.00 Cristian Micheletti (Sissa)<\/p>\n\n\n\n

When knots and plectonemes: DNA translocation with a twist<\/em><\/p>\n\n\n\n

15.15-15.45 Nicoletta Plotegher (UniPd)<\/p>\n\n\n\n

Nanobodies as allosteric modulators of glucocerebrosidase activity and stability: a novel therapeutic approach for Parkinson’s and Gaucher disease?<\/em><\/p>\n\n\n\n

16.00-16.30 Pietro Sormanni (Imperial College, UK)<\/p>\n\n\n\n

Antibody discovery and Engineering by Computational Design<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

17.00-17.45  short talks<\/em>:<\/p>\n\n\n\n

<\/em>Enrico Formasa (Sissa), Scalable Monte Carlo Assembly of polymer melts<\/em><\/p>\n\n\n\n

<\/em>Giulia Milordini (IIT) \u201cComputationally-designed aptamers targeting RAD51-BRCA2 interaction\u201d<\/em><\/p>\n\n\n\n

<\/em>Alessia Guadagnin Pattaro (UniTn) Functional Residues and Allosteric Pathways of Current and Ancestral Steroid Receptors highlighted using Information Theory<\/em><\/p>\n\n\n\n

<\/div>\n\n\n\n

Wednesday 11<\/strong>th<\/sup><\/strong><\/p>\n\n\n\n

9.00-9.30 Fabrizio Chiti (UniFi)<\/p>\n\n\n\n

Polymorphism\u00a0of\u00a0amyloid\u00a0fibrils\u00a0in the\u00a0Amyloid\u00a0Atlas.\u00a0Comparison\u00a0with\u00a0predictive\u00a0algorithms<\/em><\/p>\n\n\n\n

9.45-10.15 Paolo De Los Rios (EPFL, Switzerland)<\/p>\n\n\n\n

The two-step force-generating mechanism of Hsp70<\/em><\/p>\n\n\n\n

10.30-11.00 Nick Gilbert (U. of Edinburgh)<\/p>\n\n\n\n

Understanding a crystalline to liquid-like phase transition in chromatin<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

11.30-12.00 Nikolay Dokholyan (U. of Virginia)<\/p>\n\n\n\n

Nanocomputing Agents \u2014 Hacking Cellular Behavior<\/em><\/p>\n\n\n\n

12.15-12.45 Stefania Brocca (UniMib)<\/p>\n\n\n\n

Engineering condensate stability: from charge patterning design to non-native solvent tolerance<\/em><\/em><\/p>\n\n\n\n

lunch break<\/em><\/p>\n\n\n\n

14.30-15.00 Francesco Zamponi (La Sapienza)<\/p>\n\n\n\n

Emergent time scale of epistasis in protein evolution<\/em><\/p>\n\n\n\n

15.15-15.45 Benedetta Bolognesi (Barcelona)<\/p>\n\n\n\n

Deep mutagenesis to extract mechanistic insights into amyloid transition states<\/em><\/p>\n\n\n\n

16.00-16.30 Riccardo Capelli (UniMi)<\/p>\n\n\n\n

Mechanistic insights on Class A GPCRs activity from Constant-pH Simulations<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

17.00-17.45  short talks<\/em>:<\/p>\n\n\n\n

<\/em>Waad AlBawardi (Edinburgh) Nucleosome positioning modulates chromatin dynamic and phase behaviour<\/em><\/p>\n\n\n\n

Davide Revignas (UniPd), Entangled motifs impose specific constraints on good-folding sequences in lattice protein models.<\/em><\/p>\n\n\n\n

<\/em>Olivier Languid-Catto\u00ebn (SISSA), Sampling and validation of RNA-Mg\u00b2<\/em>\u207a binding sites with Molecular Dynamics<\/em><\/p>\n\n\n\n

<\/div>\n\n\n\n

Thursday 12<\/strong>th<\/sup><\/strong><\/p>\n\n\n\n

9.00-9.30 Gian Gaetano Tartaglia (IIT)<\/p>\n\n\n\n

Aptmers for protein aggregation inhibition<\/em><\/p>\n\n\n\n

9.45-10.15 Alfonso De Simone (UniNa)<\/p>\n\n\n\n

Elucidating the Role of Protein Disorder in Aggregation and Phase Separation<\/em><\/p>\n\n\n\n

10.30-11.00 Matteo Cagiada (Copenhagen and Oxford)<\/p>\n\n\n\n

Towards improved predictions of protein dynamics: from side-chain motions to loop flexibility using generative models<\/em><\/p>\n\n\n\n

coffee break<\/em><\/p>\n\n\n\n

11.30-12.00 Roberto Battistutta (UniPd)<\/p>\n\n\n\n

Dynamics and allostery from the crystal structure ensamble of SARS-CoV-2 Mpro<\/em><\/p>\n\n\n\n

12.15-12.45 short talks<\/em>: <\/p>\n\n\n\n

Salvatore Di Marco (SISSA), Toward Efficient RNA Sampling: Refining Solute Tempering Protocols<\/em><\/p>\n\n\n\n

Nicola Perotti (UniTn), Designing High-Affinity YTH Mutants for Sequence-Specific RNA Recognition<\/em><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Monday 9th 14.15-14.30 Welcome 14.30-15.00 Gabriella Heller (UCL, UK) Small-molecule binding to disordered proteins 15.15-15.45 Gianluca Lattanzi (UniTn) Exploring Biological Complexity through Molecular Simulations 16.00-16.30 Davide Mazza (U. San Raffaele, Milano) Probing transcription factors at single molecule level in living cells: search mechanism and non-equilibrium kinetics coffee break 17.00-17.30 Alessandro Angelini (UniVe) Synergistic evolution of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-63","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/pages\/63","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/comments?post=63"}],"version-history":[{"count":130,"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/pages\/63\/revisions"}],"predecessor-version":[{"id":399,"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/pages\/63\/revisions\/399"}],"wp:attachment":[{"href":"https:\/\/sites.unimi.it\/bressanone\/wp-json\/wp\/v2\/media?parent=63"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}