{"id":2901,"date":"2023-01-07T18:35:42","date_gmt":"2023-01-07T17:35:42","guid":{"rendered":"http:\/\/sites.unimi.it\/foodsystems\/?p=2901"},"modified":"2026-01-19T16:28:15","modified_gmt":"2026-01-19T15:28:15","slug":"phd-student-profile-agostina-colacicco","status":"publish","type":"post","link":"https:\/\/sites.unimi.it\/foodsystems\/2023\/01\/07\/phd-student-profile-agostina-colacicco\/","title":{"rendered":"PhD student profile, Agostina Colacicco"},"content":{"rendered":"<div class=\"entry\">\n<p><strong>PhD Student<\/strong>: Agostina Colacicco (ORCID n. <a href=\"https:\/\/orcid.org\/0000-0003-2780-0668\" target=\"_blank\" rel=\"noopener\">0000-0003-2780-0668<\/a>)<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2903\" src=\"http:\/\/sites.unimi.it\/foodsystems\/wp-content\/uploads\/2023\/01\/Foto-Colacicco-Agostina.jpeg\" alt=\"\" width=\"200\" height=\"200\" srcset=\"https:\/\/sites.unimi.it\/foodsystems\/wp-content\/uploads\/2023\/01\/Foto-Colacicco-Agostina.jpeg 200w, https:\/\/sites.unimi.it\/foodsystems\/wp-content\/uploads\/2023\/01\/Foto-Colacicco-Agostina-150x150.jpeg 150w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/p>\n<p><strong>Supervisor<\/strong>: Dr. Martina Letizia Contente (DeFENS)<\/p>\n<p><strong>Co-tutor<\/strong>: Prof. Francesco Molinari<\/p>\n<p><strong>Dean<\/strong>: Prof. Diego Mora<\/p>\n<p><strong>PhD title achieved on<\/strong>: 19<sup>th<\/sup> December 2025<\/p>\n<p><strong>Research area<\/strong>: Chemistry and Biochemistry<\/p>\n<p><strong>Research topic: <\/strong><\/p>\n<p>From agriculture residues to high-value products: green approaches for their extraction, (bio)transformation and large scale preparation<\/p>\n<p><strong>Project Synopsis:<\/strong><\/p>\n<p>Starting from agricultural waste (e.g., soy plant residues, olive trees, vanilla plants, and citrus plant residues), green technologies will be used for the extraction and transformation of key glycosides.<\/p>\n<p>Employing extremophilic enzymes, the corresponding aglycones possessing higher bioactive effects on human health as antioxidants and anti-inflammatory compounds will be obtained. According to FDA and EMA regulations, processing these molecules through biocatalytic approaches allows them to be considered and commercialized as natural.<\/p>\n<p>After a batch mode optimization, process implementation will be carried out by employing enzyme immobilization techniques and biocatalyst incorporation in flow chemistry reactors. The combination of these two strategies allows for improved catalyst stability and increased process sustainability and productivity.<\/p>\n<p><strong>Project keywords: <\/strong><\/p>\n<p>Waste recycling, biocatalysis, enzyme immobilization, flow chemistry.<\/p>\n<p><strong>Contacts<\/strong><\/p>\n<p><em>laboratory address<\/em>: Via Celoria 2, 20133 Milano Department of Food, Environmental and Nutritional Sciences (DeFENS)<\/p>\n<p><em>email address<\/em>: <a href=\"mailto:agostina.colacicco@unimi.it\">agostina.colacicco@unimi.it<\/a><\/p>\n<p><strong>Collaborations<\/strong><\/p>\n<p>Prof. Stefano Farris DEFENS<\/p>\n<p><strong>Sponsor<\/strong><\/p>\n<p><em>Fellowship sponsor<\/em>: Universit\u00e0 degli Studi di Milano (PNRR funded project \u201cAGRITECH\u201d Spoke 8)<\/p>\n<p><em>Project sponsor<\/em>: Universit\u00e0 degli Studi di Milano (PNRR funded project \u201cAGRITECH\u201d Spoke 8)<\/p>\n<p><strong>Publications<\/strong><\/p>\n<p>Donzella, S., <strong>Colacicco, A.<\/strong>, Nespoli, L., &amp; Contente, M. L. (2022). Mimicking Natural Metabolisms: Cell\u2010Free Flow Preparation of Dopamine. ChemBioChem, 23(24), e202200462. (<a href=\"https:\/\/doi.org\/10.1002\/cbic.202200462\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1002\/cbic.202200462<\/a>)<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>PhD Student: Agostina Colacicco (ORCID n. 0000-0003-2780-0668) Supervisor: Dr. Martina Letizia Contente (DeFENS) Co-tutor: Prof. Francesco Molinari Dean: Prof. Diego Mora PhD title achieved on: 19th December 2025 Research area: Chemistry and Biochemistry Research topic: From agriculture residues to high-value products: green approaches for their extraction, (bio)transformation and large scale preparation Project Synopsis: Starting from &#8230;<\/p>\n","protected":false},"author":1,"featured_media":2903,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[93,59],"tags":[317,318,316],"class_list":{"0":"post-2901","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-news","8":"category-phd-student-profile","9":"tag-enzyme-immobilization","10":"tag-flow-chemistry","11":"tag-waste-recycling","12":"anons"},"modified_by":"admin","_links":{"self":[{"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/posts\/2901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/comments?post=2901"}],"version-history":[{"count":4,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/posts\/2901\/revisions"}],"predecessor-version":[{"id":3856,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/posts\/2901\/revisions\/3856"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/media\/2903"}],"wp:attachment":[{"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/media?parent=2901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/categories?post=2901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.unimi.it\/foodsystems\/wp-json\/wp\/v2\/tags?post=2901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}