OrganicSynthesis

Research Activity

Homogeneous transition metal catalysis: i) asymmetric catalysis; ii) design and synthesis of supramolecular catalysts; iii) development of sustainable and efficient reduction methodologies (iron catalyzed reductions, asymmetric hydrogenation of pyridines and tandem metathesis-hydrogenation processes).

Synthesis of targeted cytotoxic agents: development of new peptide / peptidomimetic ligands of tumor-associated receptors (e.g. integrins and vascular endothelial growth factor receptors) and their conjugation to cytotoxic, pro-apoptotic or fluorescent compounds for tumor diagnosis and therapy.