Research Activity
Homogeneous transition metal catalysis: i) asymmetric catalysis; ii) design and synthesis of supramolecular catalysts; iii) development of sustainable and efficient reduction methodologies (iron catalyzed reductions, asymmetric hydrogenation of pyridines and tandem metathesis-hydrogenation processes).
Synthesis of targeted cytotoxic agents: development of new peptide / peptidomimetic ligands of tumor-associated receptors (e.g. integrins and vascular endothelial growth factor receptors) and their conjugation to cytotoxic, pro-apoptotic or fluorescent compounds for tumor diagnosis and therapy.
News
Latest Publications
"RGD Cyclopeptide Equipped with a Lysine-Engaging Salicylaldehyde Showing Enhanced Integrin Affinity and Cell Detachment Potency" - G. Sacco, C. Gennari et al. Chem. Eur. J. 2023, DOI: 10.1002/chem.202203768
"Metallaphotoredox C−O and C−N Cross-Coupling Using Donor-Acceptor Cyanoarene Photocatalysts" - T. Gandini, L. Pignataro et al. ChemCatChem 2022, DOI: 10.1002/cctc.202200990