Year 2024
Porro, A.; Armano, E.; Brandalise, F.; Appiani, R.; Beltrame, M.; Saponaro, A.; Dallanoce, C.; Nakajo, K.; Ryu, K.; Leone, R.; Thiel, G.; Pallavicini, M.; Moroni, A.; Bolchi, C. A Photoactivatable Version of Ivabradine Enables Light-Induced Block of HCN Current In Vivo. Journal of Medicinal Chemistry, 2024, 67(18), 16209–16221
Armano, E.; Giraudo, A.; Morano, C.; Pallavicini, M.; Bolchi, C. 3-Ethoxycarbonyl-1,4-benzodioxin-2-carboxylic Acid. Molbank, 2024, 3, M1873
Appiani, R.; Viscarra, F.; Biggin, P.C.; Bermudez, I.; Giraudo, A.; Pallavicini, M.; Bolchi, C. Selective Potentiation of the (α4)3(β2)2 Nicotinic Acetylcholine Receptor Response by NS9283 Analogues. ACS Chemical Neuroscience, 2024, 15(7), 1501–1514
Year 2023
Armano, E.; Giraudo, A.; Morano, C.; Pallavicini, M.; Bolchi, C. 3-Ethoxycarbonyl-1,4-benzodioxin-2-carboxylic Acid. Molbank, 2024, 3, M1873
Appiani, R.; Viscarra, F.; Biggin, P.C.; Bermudez, I.; Giraudo, A.; Pallavicini, M.; Bolchi, C. Selective Potentiation of the (α4)3(β2)2 Nicotinic Acetylcholine Receptor Response by NS9283 Analogues. ACS Chemical Neuroscience, 2024, 15(7), pp. 1501–1514
Bolchi, C.; Pallavicini, M. Addressing Motor Dysfunction by a Selective α6-Containing Nicotinic Receptor Antagonist. Journal of Medicinal Chemistry, 2023, 66(21), 14494–14496
Giraudo, A.; Armano, E.; Morano, C.; Pallavicini, M.; Bolchi, C. Green Oxidation of Heterocyclic Ketones with Oxone in Water. Journal of Organic Chemistry, 2023, 88(21), 15461–15465
Giraudo, A.; Pallavicini, M.; Bolchi, C. Small molecule ligands for α9 * and α7 nicotinic receptors: A survey and an update, respectively. Pharmacological Research, 2023, 193, 106801
Armano, E.; Giraudo, A.; Morano, C.; Pallavicini, M.; Bolchi, C. Methyl 8- and 5-Nitro-1,4-Benzodioxane-2-Carboxylate. Molbank, 2023, 2, M1661
Armano, E.; Giraudo, A.; Pallavicini, M.; Bolchi, C. Methyl 8- and 5-Bromo-1,4-Benzodioxane-2-carboxylate: Unambiguous Identification of the Two Regioisomers. Molbank, 2023, 2, M1623
Bhavsar, P.; Zoccola, M.; Dalla Fontana, G.; Pallavicini, M.; Roda, G.; Bolchi, C. Sustainable Routes for Wool Grease Removal Using Green Solvent Cyclopentyl Methyl Ether in Solvent Extraction and Biosurfactant Wool Protein Hydrolyzate in Scouring. Processes, 2023, 11(5), 1309
Morano, C.; Dei Cas, M.; Bergamaschi, R.F.; Palmisano, E.; Pallavicini, M.; Bolchi, C.; Roda, G.; Casati, S. Fractioning and Compared 1H NMR and GC-MS Analyses of Lanolin Acid Components. Molecules, 2023, 28(4), 1635
Bavo, F.; Pallavicini, M.; Pucci, S.; Appiani, R.; Giraudo, A.; Oh, H.; Kneisley, D.L.; Eaton, B.; Lucero, L.; Gotti, C.; Clementi, F.; Whiteaker, P. Subnanomolar Affinity and Selective Antagonism at α7 Nicotinic Receptor by Combined Modifications of 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624). Journal of Medicinal Chemistry, 2023, 66(1), 306-332
Mattioli, L.B.; Corazza, I.; Micucci, M.; Pallavicini, M.; Budriesi, R. Tannins-Based Extracts: Effects on Gut Chicken Spontaneous Contractility. Molecules, 2023, 28(1), 395
Year 2022
Giurato, D.; Correddu, D.; Catucci, G.; Di Nardo, G.; Bolchi, C.; Pallavicini, M.; Gilardi, G. Design of a H2O2-generating P450SPα fusion protein for high yield fatty acid conversion. Protein Science, 2022, 31(12)
Morano, C.; Dei Cas, M.; Roda, G.; Fabbriconi, A.; Casagni, E.; Pallavicini, M.; Bolchi, C.; Pallotti, G.; Romaniello, F.; Rovellini, P. The Antioxidant Role of Hemp Phytocomplex in Cannabis Oil-Based Extracts. Pharmaceuticals, 2022, 15(9), 1102
Bavo, F.; Pallavicini, M.; Pucci, S.; Appiani, R.; Giraudo, A.; Eaton, B.; Lucero, L.; Gotti, C.; Moretti, M.; Whiteaker, P.; Bolchi, C. From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human α9α10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue. Journal of Medicinal Chemistry, 2022, 65(14), 10079-10097
Appiani, R.; Pallavicini, M.; Hamouda, A.K.; Bolchi, C. Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries. Bioorganic and Medicinal Chemistry Letters, 2022, 65, 128701
Appiani, R.; Morano, C.; Roda, G.; Pallavicini, M.; Bolchi, C. 4-, 5-, 6-, and 7-Hydroxybenzofuran: a unified strategy for a two-step synthesis of versatile benzofuranic building blocks. Arkivoc, 2022, 5, 259-269
Pucci, S.; Bolchi, C.; Bavo, F.; Pallavicini, M.; De Palma, C.; Renzi, M.; Fucile, S.; Benfante, R.; Di Lascio, S.; Lattuada, D.; Bessereau, J.; D’Alessandro, M. Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells. Pharmacological Research, 2022, 175, 105959
Year 2021
Bertolini, V.; Pallavicini, M.; Tibhe, G.; Roda, G.; Arnoldi, S.; Monguzzi, L.; Zoccola, M.; Di Nardo, G.; Gilardi, G.; Bolchi, C. Synthesis of α-Hydroxy Fatty Acids from Fatty Acids by Intermediate α-Chlorination with TCCA under Solvent-Free Conditions: A Way to Valorization of Waste Fat Biomasses. ACS Omega, 2021, 6 (47), 31901-31906.
Bertolini, V.; Appiani, R.; Pallavicini, M.; Bolchi, C. Green Oxidation of Ketones to Lactones with Oxone in Water. Journal of Organic Chemistry, 2021, 86(21), 15712-15716
Dei Cas, M.; Arnoldi, S.; Monguzzi, L.; Casagni, E.; Morano, C.; Vieira de Manincor, E.; Bolchi, C.; Pallavicini, M.; Gambaro, V.; Roda, G. Characterization of chemotype-dependent terpenoids profile in cannabis by headspace gas-chromatography coupled to time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2021, 203, 114180
Bavo, F.; Pallavicini, M.; Appiani, R.; Bolchi, C. Determinants for α4β2 vs. α3β4 subtype selectivity of pyrrolidine-based nachrs ligands: A computational perspective with focus on recent cryo-em receptor structures. Molecules, 2021, 26(12), 3603
Micucci, M.; Budriesi, R.; Aldini, R.; Fato, R.; Bergamini, C.; Vivarelli, F.; Canistro, D.; Bolchi, C.; Chiarini, A.; Rizzardi, N.; Pallavicini, M.; Frosini, M.; Angeletti, A. Castanea sativa Mill. bark extract cardiovascular effects in a rat model of high-fat diet. Phytotherapy Research, 2021, 35(4), 2145-2156
Bolchi, C.; Pallavicini, M.; Casagni, E.; Vieira de Manincor, E.; Gambaro, V.; Dei Cas, M.; Roda, G. Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches. Analytical Sciences, 2021, 37(12), 1665-1673
Bolchi, C.; Appiani, R.; Roda, G.; Bertolini, V.; Arnoldi, S.; Pallavicini, M. Efficient conversion of D-mannitol into 1,2:5,6-diacetonide with Aquivion-H as a recyclable catalyst. Carbohydrate Research, 2021, 499, 108229
Year 2020
Bavo, F.; Pallavicini, M.; Gotti, C.; Appiani, R.; Moretti, M.; Colombo, S. F.; Pucci, S.; Viani, P.; Budriesi, R.; Renzi, M.; Fucile, S.; Bolchi, C. Modifications at C(5) of 2-(2-pyrrolidinyl)-substituted 1,4-benzodioxane elicit potent α4β2 nicotinic acetylcholine receptor partial agonism with high selectivity over the α3β4 subtype. Journal of Medicinal Chemistry, 2020, 63(24), 15668-15692
Bolchi, C.; Bavo, F.; Appiani, R.; Roda, G.; Pallavicini. M. 1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry: A review of its recent applications in drug design. European Journal of Medicinal Chemistry, 2020, 200, 112419
Braida, D.; Ponzoni, L.; Moretti, M.; Viani, P.; Pallavicini, M.; Bolchi, C.; Appiani, R.; Bavo, F.; Gotti, C.; Sala, M. Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors. Psychopharmacology, 2020, 237(8), 2317–2326
Micucci, M.; Bolchi, C.; Budriesi, R.; Cevenini, M.; Maroni, L.; Capozza, S.; Chiarini, A.; Pallavicini, M.; Angeletti, A. Antihypertensive phytocomplexes of proven efficacy and well-established use: Mode of action and individual characterization of the active constituents. Phytochemistry, 2020, 170, 112222
Airoldi, V.; Piccolo, O.; Roda, G.; Appiani, R.; Bavo, F.; Tassini, R.; Paganelli, S.; Arnoldi, S.; Pallavicini, M.; Bolchi, C. Efficient One-Pot Reductive Aminations of Carbonyl Compounds with Aquivion-Fe as a Recyclable Catalyst and Sodium Borohydride. European Journal of Organic Chemistry, 2020, 2020(2), 162–168
Year 2019
Roda, G.; Faggiani, F.; Bolchi, C.; Pallavicini, M.; Dei Cas, M. Ten Years of Fentanyl-like Drugs: a Technical-analytical Review. Analitycal Sciences, 2019, 35 (5), 479-491
Year 2018
Bolchi, C.; Roda, G.; Pallavicini, M. 1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization, Amino Acids, 2018, 50 (12), 1759-1767
Bavo, F.; Pucci, S.; Fasoli, F.; Lammi, C.; Moretti, M.; Mucchietto, V.; Lattuada D.; Viani, P.; De Palma, C; Budriesi, R., Corradini, I.; Dowell, C.; McIntosh, JM.; Clementi, F., Bolchi, C.; Gotti, C.; Pallavicini, M. Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan, Journal of Medicinal Chemistry, 2018, 61 (23), 10531-10544
Bolchi, C.; Bavo, F.; Regazzoni, L.; Pallavicini, M. Preparation of enantiopure methionine, arginine, tryptophan, and proline benzyl esters in green ethers by Fischer–Speier reaction, Amino Acids, 2018, 50 (9), 1261-1268
Mucchietto, V.; Fasoli, F.; Pucci, S.; Moretti, M.; Benfante, R.; Maroli, A.; Di Lascio, S.; Bolchi, C.; Pallavicini, M.; Dowell, C.; McIntosh, M.; Clementi, F.; Gotti, C. α9- and α7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line, British Journal of Pharmacology, 2018, 175 (11), 1957-1972
Faré, F.; Dei Cas, M.; Arnoldi, S.; Casagni, E.; Visconti, G.L.; Parnisari, G.; Bolchi, C.; Pallavicini, M.; Gambaro, V.; Roda, G. Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up, European Journal of Lipid Science and Technology, 2018, 120 (4), 1700525
Bolchi, C.; Roda, G.; Pallavicini, M. Simple route to synthesize (E)-3-propyl-4-oxo-2-butenoic acid esters through the Z isomer, Synthetic Communications, 2018, 48 (1), 85-90
Year 2017
Bolchi, C.; Bavo, F.; Pallavicini, M. Preparation and unequivocal identification of the regioisomers of nitrocatechol monobenzyl ether, Synthetic Communications, 2017, 47 (16), 1507-1513
Bolchi, C.; Bavo, F.; Pallavicini, M. One-step preparation of enantiopure L- or D-amino acid benzyl esters avoiding the use of banned solvents, Amino Acids, 2017, 49 (5), 957-974
Bolchi, C.; Bavo, F.; Gotti, C.; Fumagalli, L.; Fasoli, F.; Binda, M.; Mucchietto, V.; Sciaccaluga, M.; Plutino, S.; Fucile, S.; Pallavicini, M. From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor, European Journal of Medicinal Chemistry, 2017, 125, 1132-1144
Bolchi, C.; Bavo, F.; Pallavicini, M. Phase Diagrams to Evaluate the Opportunity for Enantiomeric Enrichment of Some Nonracemic Mixtures of Amino Acid Benzyl Esters by Crystallization as p-Toluenesulfonate Salts, Organic Process Research & Development, 2017, 21 (11), 1752-1757
Year 2016
Straniero, V.; Pallavicini, M.; Chiodini, G.; Zanotto, C.; Volontè, L.; Radaelli, A.; Bolchi, C.; Fumagalli, L.; Sanguinetti, M.; Menchinelli, G.; Delogu, G.; Battah, B.; De Giuli Morghen, C. Valoti, E. 3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division, European Journal of Medicinal Chemistry, 2016, 120, 227-243
Fumagalli, L.; Bolchi, C.; Bavo, F.; Pallavicini, M. Crystallization-based resolution of 1,4-benzodioxane-2-carboxylic acid enantiomers via diastereomeric 1-phenylethylamides, Tetrahedron Letters, 2016, 57 (18), 2009-2011
Bolchi, C.; Bavo, F.; Fumagalli, L.; Gotti, C.; Fasoli, F.; Moretti, M.; Pallavicini, M. Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands, Bioorganic & Medicinal Chemistry Letters, 2016, 26 (23), 5613-5617
Colciago, A.; Mornati, O.; Ferri, N.; Castelnovo, L.F.; Fumagalli, L.; Bolchi, C.; Pallavicini, M.; Valoti, E.; Negri-Cesi, P. A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility “in vitro”, Pharmaceutical Research, 2016, 103, 215-226
