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The Synthesis of (+)-Dumetorine and Congeners Using Flow Chemistry Technologies

E. Riva, A. Rencurosi, S. Gagliardi, D. Passarella, M. Martinelli

  1. Chemistry: a European Journal (2011), 17, 6221 – 6226

Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors

M. Christodoulou, F. Colombo, D. Passarella, G. Ieronimo, V. Zuco, M. De Cesare, F. Zunino

Bioorg. Med. Chem. (2011), 15, 1649-1657

Enantiopure 2-piperidylacetaldehyde as useful building block in the diversity-oriented synthesis of polycyclic piperidine derivative

E. Borsini, G. Broggini, F. Colombo, M. Khansaa, A. Fasana, S. Galli, D. Passarella, E. Riva, S. Riva

  1. Tetrahedron: Asymmetry (2011), 22, 264 -269

New flavonol glycosides from Aconitum burnatii Gáyer and Aconitum variegatum L.

S. Vitalini, A. Braca, D. Passarella, G. Fico

Fitoterapia (2010), 81, 940-947
DOI: 10.1016/j.fitote.2010.06.012

Exploiting enzymatic regioselectivity: A facile methodology for the synthesis of polyhydroxylated hybrid compounds

P. Magrone, F. Cavallo, W. Panzeri, D. Passarella, S. Riva

Org. Biom. Chemistry (2010), 8, 5583-5590
DOI: 10.1039/c0ob00304b

Synthesis and biological evaluation of new camptothecin derivatives obtained by modification of position 20

E. Riva, D. Comi, S. Borrelli, F. Colombo, B. Danieli, J. Borlak, L. Evensen, J.B. Lorens, G. Fontana, O.M. Gia, L. Dallavia, D. Passarella

Bioorg. Med. Chem. (2010), 18, 8660-8668
DOI: 10.1016/j.bmc.2010.09.069

Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions

E. Riva, S. Gagliardi, M. Martinelli, D. Passarella, D. Vigo, A. Rencurosi

Tetrahedron (2010), 17, 3242-3247

Synthesis and Biological Evaluation of Novel Thiocolchicine-Podophyllotoxin Conjugates

D. Passarella, B. Peretto, R. Blasco, G. Cappelletti, D. Cartelli, C. Ronchi, J. Snaith, G. Fontana, B. Danieli, J. Borlak

Eur. J. Med. Chem. (2010), 45, 219-226

Synthesis and biological evaluation of epothilone A dimeric compounds

D. Passarella, D. Comi, G. Cappelletti, D. Cartelli, J. Gertsch, A. R. Quesada, J. Borlak, K.-H. Altmann

Bioorg. Med. Chem. (2009), 17, 7435-7440.

Histone Deacetylase and Microtubules as Targets for the Synthesis of Releasable Conjugate Compounds

D. Passarella, D. Comi, A. Vanossi, G. Paganini, F. Colombo, L. Ferrante, V. Zuco, B. Danieli, F. Zunino

Bioorg. Med. Chem. Lett. (2009), 19, 6358-6363

Efficient Continuous Flow Synthesis of Hydroxamic Acids and Suberoylanilide Hydroxamic Acid Preparation.

E. Riva, S. Gagliardi, C. Mazzoni, D. Passarella, A. Rencurosi, D. Vigo, M. Martinelli

Journal of Organic Chemistry (2009), 74(9), 3540-3543.

Enantiopure N-Boc piperidine-2-ethanol for the synthesis of (+)-and (_)-dumetorine, and (+)- and (_)-epidihydropinidine

D. Passarella, Riva, S.; G. Grieco, F. Cavallo, B. Checa, F. Arioli, E. Riva, B. Danieli

Tetrahedron: Asymmetry (2009), 20, 192-197

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Department of Chemistry
Università degli Studi di Milano
Via Golgi 19
20133 Milano - Italy
Tel. +39 02 5031 4081
Fax. +39 025 031 4078
daniele.passarella@unimi.it
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