{"id":27247,"date":"2025-08-09T10:33:19","date_gmt":"2025-08-09T08:33:19","guid":{"rendered":"https:\/\/sites.unimi.it\/passalab\/?p=27247"},"modified":"2025-08-09T10:33:21","modified_gmt":"2025-08-09T08:33:21","slug":"synthesis-and-multitarget-inhibitory-effect-of-indole-based-ethyl-cinnamate-derivatives-against-sars-cov-2-mpro-and-cathepsins-for-broad-spectrum-anti-coronavirus-activity","status":"publish","type":"post","link":"https:\/\/sites.unimi.it\/passalab\/2025\/08\/09\/synthesis-and-multitarget-inhibitory-effect-of-indole-based-ethyl-cinnamate-derivatives-against-sars-cov-2-mpro-and-cathepsins-for-broad-spectrum-anti-coronavirus-activity\/","title":{"rendered":"Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro\u00a0and cathepsins for broad-spectrum anti-coronavirus activity"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.scopus.com\/pages\/publications\/105006570772#\">Bioorganic and Medicinal Chemistry<\/a> 2025, DOI: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089625001993\" data-type=\"link\" data-id=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089625001993\">10.1016\/j.bmc.2025.118258<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Andrea\u00a0Citarella,\u00a0Giulia\u00a0Sibille,\u00a0Davide\u00a0Moi,\u00a0Alessandro\u00a0Dimasi,\u00a0Tommaso\u00a0Braga,\u00a0Lorenzo Dal\u00a0Col,\u00a0Lorenzo\u00a0Ruberto,\u00a0Stefano\u00a0Pieraccini,\u00a0Maurizio\u00a0Sironi,\u00a0Nicola\u00a0Micale,\u00a0Tanja\u00a0Schirmeister,\u00a0Valerio\u00a0Fasano,\u00a0Alessandra\u00a0Silvani,\u00a0Clelia\u00a0Giannini,\u00a0Giorgio\u00a0Gribaudo,\u00a0Daniele\u00a0Passarella<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bioorganic and Medicinal Chemistry 2025, DOI: 10.1016\/j.bmc.2025.118258 Andrea\u00a0Citarella,\u00a0Giulia\u00a0Sibille,\u00a0Davide\u00a0Moi,\u00a0Alessandro\u00a0Dimasi,\u00a0Tommaso\u00a0Braga,\u00a0Lorenzo Dal\u00a0Col,\u00a0Lorenzo\u00a0Ruberto,\u00a0Stefano\u00a0Pieraccini,\u00a0Maurizio\u00a0Sironi,\u00a0Nicola\u00a0Micale,\u00a0Tanja\u00a0Schirmeister,\u00a0Valerio\u00a0Fasano,\u00a0Alessandra\u00a0Silvani,\u00a0Clelia\u00a0Giannini,\u00a0Giorgio\u00a0Gribaudo,\u00a0Daniele\u00a0Passarella<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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Dal\u00a0Col,\u00a0Lorenzo\u00a0Ruberto,\u00a0Stefano\u00a0Pieraccini,\u00a0Maurizio\u00a0Sironi,\u00a0Nicola\u00a0Micale,\u00a0Tanja\u00a0Schirmeister,\u00a0Valerio\u00a0Fasano,\u00a0Alessandra\u00a0Silvani,\u00a0Clelia\u00a0Giannini,\u00a0Giorgio\u00a0Gribaudo,\u00a0Daniele\u00a0Passarella","_links":{"self":[{"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/posts\/27247","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/comments?post=27247"}],"version-history":[{"count":1,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/posts\/27247\/revisions"}],"predecessor-version":[{"id":27248,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/posts\/27247\/revisions\/27248"}],"wp:attachment":[{"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/media?parent=27247"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/categories?post=27247"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.unimi.it\/passalab\/wp-json\/wp\/v2\/tags?post=27247"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}