Prof. Dimitrios Fessas
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Contatti: DiSTAM - sez. Chimica - Università degli Studi di Milano - Via Celoria, 2 - 20133 Milano (Italy) Tel. : (+39) - 0250319219 - Fax : (+39) - 0250319061 E-Mail: Dimitrios.Fessas@unimi.it |
Dimitrios Fessas si è laureato in Fisica presso l'Università di Napoli. E' stato titolare di due Borse di Studio annuali del CNR nell’ambito di Chimica Fisica. Ha conseguito il Dottorato di Ricerca in Scienze Chimiche presso l'Università di Napoli. Ricercatore dal 1996 e Professore Associato di Chimica Fisica dal 2005 presso il Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, Università di Milano.
Membro dell' Associazione Italiana di Calorimetria ed Analisi Termica (AICAT)
(anche come componente del Consiglio Direttivo 2005-2008, 2011-2014).
Esperto Qualificato in materia di radioprotezione (II grado, Elenco Nominativo Ministeriale No 1968) e membro dell'Associazione Nazionale Professionale Esperti Qualificati nella sorveglianza fisica di radioprotezione.
Presidente del "XXVIII National Conference on Calorimetry, Thermal Analysis and
Chemical Thermodynamics", AICAT-GICAT 2006, Milano
Principali temi di ricerca:
Tematica 1. Proprietà chimico-fisiche di sistemi alimentari e farmaceutici:
Transizioni di fase e/o conformazionali, separazione di fasi, gelatinizzazione (amido),
cristallizzazione, transizione vetrosa, ripartizione e mobilità dell'acqua, aggregazione,
matastabilità, ecc., di biopolimeri in sistemi complessi; Termodinamica e cinetica dei
processi di adsorbimento/desorbimento; Crescita e metabolismo microbico (studi mediante calorimetria isoterma).
Tematica 2. Termodinamica di macromolecole biologiche in soluzione:
Stabilità conformazionale; Fenomeni di "binding" (specifico e/o aspecifico)
macromolecola-ligando
Tematica 3: Processi di restauro e caratterizzazione di biomateriali nel ambito dei beni culturali.
Principale approccio sperimentale: Calorimetria e Analisi Termica.
Dimitrios Fessas kept his degree in Physics at the University of Naples. He was a CNR scholar fellow for two year in the field of Physical Chemistry. He achieve the PhD graduation in Chemical Sciences at the University of Naples. Research Professor since 1996 and Associate Professor of Physical Chemistry since 2005 at the Department of Food Science and Technology of the University of Milan.
Member of the Italian Association of Calorimetry and Thermal Analysis
(AICAT) also as member of the Board of Directors (2005-2008, 2011-2014).
"Qualified Expert" in Radiological Protection (II degree, Ministry
list no 1968) and is member of the National Professional Association of Italian Qualified
Experts in Radiological Protection.
Chairman of the "XXVIII National Conference on Calorimetry, Thermal Analysis and
Chemical Thermodynamics", AICAT-GICAT 2006, Milano, Italy
Main research lines:
Topic 1. Physico-chemical properties of food and pharmaceutical systems.
Phase and conformational transitions, phase separation, gelatinisation (starch),
crystallization, glass transition, water state, aggregation, meta-stability etc., of
biopolymers in complex systems; thermodynamics and kinetics of adsorption/desorption
processes; microbial growth and metabolism (studied by isothermal calorimetry).
Topic 2. Thermodynamics of biological macromolecules in solution:
Conformational stability; specific and/or aspecific macromolecule - ligand binding
phenomena.
Topic 3. Restoring processing and characterization of cultural heritage biomaterials.
Main experimental approach: Thermal Analysis and Calorimetry
Strumentazione disponibile in Laboratorio: Laboratory instrumentation at 2018:
• Isothermal titration microcalorimeter (Calvet) DAM (Setaram France);
• Thermogravimetry combined DSC TGA-DSC 111 (Setaram France);
• Microcalorimeter Micro DSC III (Setaram France);
• Calorimeter DSC C80D (Setaram France); Calorimeter DSC 6 (Perkin Elmer);
• Calorimeter DSC 20 (Mettler);
• Isothermal titration nano calorimeter Nano-ITC III Model 5300 (CSC USA);
• Nano Calorimeter Nano-DSC Model 6300 (CSC USA);
• Modulated Scanning Calorimeter DSC 2920 (TA Instruments);
• Modulated Adiabatic Scanning Calorimeter MASC 2 (CNR - IPCF T-lab Pisa, Italy);
• CD Spectropolarimeter J-810 (Jasco Corporation, Japan);
• Texture Analyzer TA-Hdi (Stable Micro Systems, UK)
Attività didattica 2018-2019
Elementi di Chimica e Chimica Fisica, per il Corso di Laurea in Scienze e Tecnologie della Ristorazione (I e II semestre, 8 CFU)
Elementi di Chimica e Chimica Fisica, per il Corso di Laurea in Scienze e Tecnologie Alimentari (mod. 2 Chimica Fisica II semestre), (per il mod.1 vedi prof. Molinari) (Esame unico tot 8 CFU)
Corso di Calorimetria e Analisi Termica, per la Laurea Magistrale in Scienze e Tecnologie per lo studio e la conservazione dei beni culturali e dei supporti della informazione (Classe LM-11 6 CFU)
Corsi di anni precedenti
Elementi di fisica e fisica tecnica mod. 1: fisica per il Corso di Laurea in Scienze e Tecnologie Alimentari. (II semestre, 6 CFU)
Chimica Fisica Biologica per il Corso di Laurea Specialistica in Biotecnologie Vegetali, Alimentari e Agroambientali. (II semestre, 6 CFU)
Pubblicazioni (selezione)
“Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin.” Caldinelli L, Iametti S, Barbiroli A, Bonomi F, Fessas D, Molla G, Pilone MS, Pollegioni L. J Biol Chem. 280 (2005) 22572- 22581
“Polymorph transitions in Cocoa Butter: a quantitative DSC approach”
D. Fessas, M. Signorelli and A. Schiraldi.
J. of Thermal Analysis and Calorimetry 82 (2005) 691-702.
“Water properties in wheat flour dough II: classical and Knudsen termogravimetry approach.”D. Fessas and A. Schiraldi. Food Chemistry 90 (2005) 61-68
“Role of water displacement in starch gelatinization and gluten reticolation in breadmaking:Review of research” A. Schiraldi and D. Fessas
In Starch: From starch containing sources to isolation of starches and their applications. V.P. Yuryev, P. Tomasik, H. Ruck, eds. (2004) Nova Science Publishers. Inc. ISBN 1-59454-014-4
“The role of water in dough formation and bread quality” A. Schiraldi and D. Fessas. In “Bread making, improving quality” (2003) Stanley P. Cauvain Ed.s Cambridge UK , Woodhead Publishing Ltd. ISBN 1 85573 553 9
“Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase” L. Pollegioni, S. Iametti, D. Fessas, L. Caldinelli, L. Piubelli, A.Barbiroli, M. S. Pilone F. Bonomi. Protein Science 12 (2003) 1018-1029
“Interactions between Arabinoxylans and Wheat Proteins”. D. Fessas and A. Schiraldi. Food Chemistry (2003) in print (ref. FOCH3504)
“Classical and Knudsen Thermogravimetry to check States and Displacements of Water in Food Systems” Alberto Schiraldi and Dimitrios Fessas J. of Thermal Analysis and Calorimetry 71 (2003) 221-231.
“Xanthan and Glucomannan Mixtures: Synergistic Interactions and Gelation.”
G. Paradossi, E. Chiessi, A, Barbiroli and D. Fessas Biomacromolecules 3 (2002) 498-504
“Thermal stability of the [Fe(SCys)4] site in Clostridium pasteurianum rubredoxin. Contributions of the local environment and Cys ligand protonation.” F. Bonomi, A.E. Burden, M.K. Eidsness, D. Fessas, S. Iametti, D.M. Kurtz, Jr, S. Mazzini, R.A. Scott, Q. Zeng. J. Biol. Inorg. Chem. 7 (2002) 427-436
“Effects of egg aging on baking properties of raw and pasteurised whole egg” M. Rossi, D. Fessas and C. Pompei. In proceedings of IX European Symposium on the Quality of Eggs and Egg Products, R.W.A.W. Mulder, S.F. Bilgili eds. Turkey (2001) p. 363-367 (ISBN 975-97654-0-3)
“Restoring Process and Characterisation of Ancient Damaged Parchments” A. Facchini, M.F Fancinelli, A. Bairati, C.E. Bottani, P.L. Cavallotti, D. Fessas, A. Schiraldi, G. Zerbi. Quinio 3 (2001) 51-70
“Thermal Unfolding of Monomeric and Dimeric Betalactoglobulins”D. Fessas, S. Iametti, A. Schiraldi, F. Bonomi. Eur. J. Biochemistry 268 (2001) 5439-5448
"State Diagrams of Arabinoxylan-Water Binaries" D. Fessas and A. Schiraldi, Thermochimica Acta 370, (2001) 83-89
"Isothermal Calorimetry Approach to Evaluate the Shelf-Life of Foods" M. Riva, D. Fessas, A. Schiraldi, Thermochimica Acta 370 (2001) 73-81
"Water properties in wheat flour dough I: classical termogravimetry approach." Dimitrios Fessas and Alberto Schiraldi, Food Chemistry 72 (2001) 237-244
"Starch Retrogradation In Cooked Pasta And Rice" M. Riva, D. Fessas, A.Schiraldi , Cereal Chem. 77 (2000) 433-438
" Calorimetric, biochemical and morphological investigations to validate a restoration method of fire injured ancient parchment "' D. Fessas, A. Schiraldi , R. Tenni, L. Vitellaro Zuccarello , A. Bairati and A. Facchini, Thermochimica Acta 348, (2000) 129-137
"Starch Gelatinization Kinetics in Bread Dough: DSC investigations on "simulated" baking processes" Dimitrios Fessas and Alberto Schiraldi, J. of Thermal Analysis and Calorimetry, 61 (2000) 411-423
"Mechanism of Bread Staling: an Overview" Alberto Schiraldi and Dimitrios Fessas In "Bread Staling" Y. Vodovotz and P. Chinachoti Eds. CRC publ. USA (2000) 1-17
(ISBN 0-8493-8790-6)
" Thermal stability of Clostridium pasteurianum rubredoxin: deconvoluting the contributions of the metal site and the protein " F. Bonomi, D. Fessas, S. Iametti, D.M. Kurtz, Jr, S. Mazzini, Protein Science 9 (2000) 2413-2426
"Evaluation of an Egg Product Shelf Life with Calorimetric and Classical Techiques" M. Riva and D. Fessas, In : Proceedings of VIII European Symposium on the Quality of Eggs and Egg Products, L.G. Cavalchini, D. Baroli, eds (1999) Vol. 2, p. 521-527
" Thermal Analyses In Foods And Food Processes" A. Schiraldi, L. Piazza, D. Fessas and M. Riva In "Handbook of Thermal Analysis" R.B. Kemp Editor, (1999) Volume 4: "From Macromolecules to Man", Chapter 16, 829-921, Elsevier Science B.V.
"Analisi Termica dei Prodotti Dolciari" Dimitrios Fessas Lab. 2000 (Duemila) (1999) 2 54-57 (Giornale recensito dai Chemical Abstracts)
"Applicazione di tecniche chimico-fisiche innovative per la caratterizzazione di fette biscottate" M. Riva, D. Fessas In "Ricerche e innovazioni nell'industria alimentare. Vol III", Chiriotti Editori,( 1998) p.730-738
"Texture and staling of wheat bread crumbs: effect of water extractable protein and pentosans." Dimitrios Fessas and Alberto Schiraldi. Thermochimica Acta, 323 (1998) 17-26
" g - Radiation effects on the thermal stability of bovine g - globulin." D. Fessas, K. Ciesla and A. Schiraldi., J.Thermal Analysis, 52 (1998) 745-751
"Calorimetric characterization of different yeast strains in doughs." M. Riva, D. Fessas, L. Franzetti and A. Schiraldi, J.Thermal Analysis, 52 (1998) 753-764
"TTT Diagrams for bread doughs with added hydrocolloids" L. Piazza, A. Schiraldi And D. Fessas, in Engineering and Food at Icef 7 , ed. R. Jowitt (1997) H9, Sheffield Academic Press.
"Crystallization kinetics of the cocoa butter. A calorimetric approach." A. Schiraldi, D. Fessas, E. Scavino. Revista de Ciencia (Institut d’Estudis Baleárics) 20 (1997) 95
"DSC studes on bovine serum albumin denaturation. Effects of ionic strength and SDS concentration." C. Ciancola, C. De Sena, D. Fessas, G. Graziano, G. Barone. Int. J. Biol. Macromol. 20 (1997) 193-204
"Effects of temperature and SDS on the structure of b-glycosidase from the thermophilic archaeon Sulfolobus solfataricus" S. D’auria, R. Barone, M. Rossi, R.Nucci, G. Barone, D. Fessas, E. Bertoli, and F. Tanfani, Biochem. J. 323, (1997), 833-840
"Stability of a thermophilic TIM-barrel enzyme: indoleglycerol-phosphate synthase from the thermophilic arcaeon Sulfolobus solfataricus. " G. Andreotti, M.V. Cubellis, M. di Palo, D. Fessas, G. Sannia and G. Marino, Biochem. J. 323 (1997) 259-264
"Thermodynamics of the interaction of a-cyclodextrins with carboxylic acids in aqueous solutions. A calorimetric study at 25 °C." G. Castronuovo, V. Elia, D. Fessas, A. Giordano, F. Velleca, Carbohydrate Research 287 (1996) 127-138
"Effect of osmoregulatory solytes on the thermal stability of calf thymus DNA" G. Barone, P. Del Vecchio, D.Esposito, D. Fessas, G.Graziano, J. Chem.Soc. Faraday Trans., 1996, 92(8), 1361-1367
"Deconvolution of DSC denaturation profiles of DNAs from some phages. " D. Fessas, C. De Sena, D. Esposito, G. Barone, extended abstract for J.C.A.T. 95, Marseille 22-24 mai 1995 p. 173-178, 26émes Journées de Calorimétrie et d'Analyse Thermique A.F.C.A.T.
"Surfactant binding to bovine serum albumine: a DSC study. " G.Barone, S.Capasso, P.Del Vecchio, C.De Sena, D. Fessas, C.Giancola, G.Graziano extended abstract for J.C.A.T. 95, Marseille 22-24 mai 1995 p. 173-178, 26émes Journées de Calorimétrie et d'Analyse Thermique A.F.C.A.T.
"Thermodynamics of the unfolding of some ribonucleases. " G.Barone, F.Catanzano, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, A.Riccio extended abstract for J.C.A.T. 95, Marseille 22-24 mai 1995 p. 21-25, 26émes Journées de Calorimétrie et d'Analyse Thermique A.F.C.A.T.
"Thermal denaturation of Bovine Serum Albumin and its oligomers and derivatives. II: pH dependence. " G.Barone, S.Capasso, P.Del Vecchio, C.De Sena, D. Fessas, C.Giancola, G.Graziano, P.Tramonti, J.Thermal Analysis, 45 (1995)
"Ingoing-wave boundary- condition versus optical model trasmission coefficients: a systematic comparison with particle emission data." M. Kildir, G. La Rana, R. Moro, A. Brondi, A. D'Onofrio, D. Fessas, E. Perillo, V. Roca, M. Romano, F. Terrasi, E. Vardaci, G. Nebbia, G. Viesti, F. Prete, Physical Review C 51, (1995) 1873-1881
"Thermodynamics of the interaction of cyclodextrins with aromatic and a ,w-amino acids in aqueous solutions. A calorimetric study at 25 °C." G. Castronuovo, V. Elia, D. Fessas, A. Giordano, F. Velleca, Carbohydrate Research, 272 (1995) 31-39
"The effect of pH on thermal stability of globular proteins: a critical insight." G. Barone, F.Catanzano, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, J.Thermal Analysis, 42 (1994) 383-395
"Thermodynamic Characterization of RNAase A in the Presence of Urea and GuHCl." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, A.Riccio, J.Thermal Analysis, 41 (1994) 1357-1370
"Ligand-Induced Biphasic Thermal Denaturation of RNAase A." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, A.Riccio, J.Thermal Analysis, 41 (1994) 1263-1276
"Denaturation of Biological Macromolecules: New Programs for the Deconvolution of DSC Measurements." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano in "Chemistry and Properties of Biomolecular Systems" N.Russo, J.Anastassopoulou and G. Barone (Eds.) Vol.II, pag. 67-78, Kluwer Ac. Pub. (1994)
"Thermal Behaviour of Three Ribonucleases." G.Barone, P. Del Vecchio, D. Fessas, C.Giancola, G.Graziano, A.Riccio in "Chemistry and Properties of Biomolecular Systems" N.Russo, J.Anastassopoulou and G.Barone (Eds.) Vol.II, pag. 49-65, Kluwer Ac. Pub. (1994)
"Moderne tecnologie per il rilevamento dell' inquinamento costiero e dello stato e dispersione delle acque interne superficiali." G.Barone, D. Fessas in "Atti del XIV Corso di aggiornamento di Tecniche per la difesa dall'inquinamento", G. Frega (Ed.) Editoriale BIOS giugno1993
"The deconvolution of multistate transition DSC curves of biological macromolecules: bovine serum albumin and bovine seminal ribonuclease." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, Thermochimica Acta, 227 (1993) 185-195
"Denaturation of ribonucleases from different sources in the presence of denaturing or stabilizing agents." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, A.Riccio in "Stability and Stabilization of Enzymes", pag. 189-196 W.J.J. van den Tweel et al. (Eds.) Elsevier, The Netherlands, 1993
"Protein Stability in Non-aqueous Media. A DSC Study." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano in "Stability and Stabilization of Enzymes", pag. 37-44 W.J.J. van den Tweel et al. (Eds.) Elsevier, The Netherlands, 1993
"A phenomenological study on the combined effect of increasing concentrations of greenhouse gases on the global warming." G.Barone, D. Fessas, G.Graziano in "Trends in Ecological Physical Chemistry", pag.127-145 D.Pitea et al. (Eds.) Elsevier, The Netherlands, 1993
"Thermal denaturation of ribonuclease T1. A DSC Study." G.Barone, P. Del Vecchio, D. Fessas, C.Giancola, G.Graziano, P.Pucci, A.Riccio, M.Ruoppolo, J.Thermal Analysis, 38 (1992) 2791-2802.
"THESEUS: a new software package for the handling and analysis of thermal denaturation data of biological macromolecules." G.Barone, P.Del Vecchio, D. Fessas, C.Giancola, G.Graziano, J. Thermal Analysis, 38 (1992) 2779-2790
WebMaster: Dimitrios Fessas - Ultima modifica: 20/05/05