Publications

Refereed publications

  1. M Barberis, A. Rappa, F. de Marinis, G. Pelosi, E. Guerini Rocco, Y. Zhan and G. Tiana, A rationale for the poor response to alectinib in a patient with adenocarcinoma of the lung harbouring a STRN-ALK fusion by Artificial Intelligence and molecular modelling. , Transl. Lung Canc. Res.  (in press) 
  2. F. Borando and G. Tiana, Effective model of protein-mediated interactions in chromatin , Phys. Rev. E  109 , 064406 (2024)  [link]
  3. N. Atinbayeva, I. Valent, F. Zenk, E. Loeser, M. Rauer, S. Herur, P. Quarato, G. Pyrowolakis, A. Gomez-Auli, G. Mittler, G. Cecere, S. Erhardt, G. Tiana, Y. Zhan, N. Iovino, Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos , EMBO Journal  43 , 2685 (2024)  [link]
  4. R. Beccaria, A. Lazzeri and G. Tiana, Predicting the binding of small molecules to proteins through invariant representation of the molecular structure , J. Chem. Inf. Model.  64 , 6758–6767 (2024)  [link]
  5. A. Zambon, R. Zecchina and G. Tiana, Structure of the space of folding protein sequences defined by large language models , Phys. Biol.  21 , 026002 (2024)  [link]
  6. L. Viverit, C. Y. Heo, L. N. Pereira, G. Tiana, Application of machine learning to cluster hotel booking curves for hotel demand forecasting , Int. J. Hospital. Manag.  111 , 103455 (2023)  [link]
  7. E. Marchi, Y. Zhan and G. Tiana, Locality of contacts determines the subdiffusion exponents in polymeric models of chromatin , Phys. Rev. E  107 , 064406 (2023)  [link]
  8. M. Tajana, A. Trovato and G. Tiana, Key interaction patterns in proteins revealed by cluster expansion of the partition function , Europ. Phys. J. E  45 , 95 (2022)  [link]
  9. P. Mach, P. I. Kos, Y. Zhan, J. Cramard, S. Gaudin, J. Tünnermann, E. Marchi, J. Eglinger, J. Zuin, M. Kryzhanovska, S. Smallwood, L. Gelman, G. Roth, E. P. Nora, G. Tiana, L. Giorgetti, Live-cell imaging and physical modeling reveal control of chromosome folding dynamics by cohesin and CTCF , Nature Genetics  54 , 1907-1918 (2022)  [link]
  10. H. I. Rösner, M. Caldarini, G. Potel, D. Malmodin, M. A. Vanoni, A. Aliverti, R. A. Broglia, B. B. Kragelund, G. Tiana, The denatured state of HIV-1 protease under native conditions , Proteins  90 , 96-109 (2022)  [link]
  11. M. Crippa, D. Andreghetti, R. Capelli and G. Tiana, Evolution of Frustrated and Stabilising Contacts in Reconstructed Ancient Proteins , Europ. Biophys. J.  50 , 699-712 (2021)  [link]
  12. F. Zenk, Y. Zhan, P. Kos, E. Loeser, N. Atinbayeva, M. Schaechtle, G. Tiana, L. Giorgetti, N. Iovino, HP1 drives de novo 3D genome reorganization in early Drosophila embryos , Nature  593 , 289-392 (2021)  [link]
  13. G. Ermondi, F. Lavore, M. Vallaro, G. Tiana, F. Vasile and G. Caron, Managing experimental 3D structures in the Beyond-Rule-of-5 chemical space: The case of rifampicin , Chemistry  27 , 10394-10404 (2021)  [link]
  14. M. Negri. G. Tiana and R. Zecchina, Native state of natural proteins optimizes local entropy , Phys. Rev. E  104 , 064117 (2021)  [link]
  15. F. Cuturello, G. Tiana and G. Bussi, Assessing the accuracy of direct-coupling analysis for RNA contact prediction , RNA Journal  26 , 637-647 (2020)  [link]
  16. S. Pigolotti, M. H. Jensen, Y. Zhan and G. Tiana, Chromosome contact maps are bifractal , Phys. Rev. Res.  2 , 043078 (2020)  [link]
  17. M. Crippa, Y. Zhan, G. Tiana, Effective model of loop extrusion predicts chromosomal domains , Phys. Rev. E  102 , 032414 (2020)  [link]
  18. M. C. Lionetti, F. Cola, O. Chepizhko, M. R. Fumagalli, F. Font-Clos, R. Ravasio, S. Minucci, P. Canziano, M. Camera, G. Tiana, S. Zapperi, C. La Porta, MicroRNA-222 regulates melanoma plasticity , J. Clin. Med.  9 , 2573 (2020)  [link]
  19. S. Terzoli and G. Tiana, Molecular Recognition Between Cadherins Studied by a Coarse-Grained Model Interacting With a Coevolutionary Potential , J. Phys. Chem. B  124 , 4079 (2020)  [link]
  20. J. Redolfi, Y. Zhan, C. Valdes-Quezada, M. Kryzhanovska, I. Guerreiro, V. Iesmantavicius, T. Pollex, R. S. Grand, E. Mulugeta, J. Kind, G. Tiana, S. A. Smallwood, W. de Laat and L. Giorgetti, DamC reveals principles of chromatin folding in vivo without crosslinking and ligation , Nature Str. Mol. Biol.  26 , 471-480 (2019)  [link]
  21. F. Vasile and G. Tiana, Determination of Structural Ensembles of Flexible Molecules in Solution from NMR data Undergoing Spin Diffusion , J. Chem. Inf. Model.  59 , 2973 (2019)  [link]
  22. S. Bonfanti, M. C. Lionetti, M. R. Fumagalli V. R Chirasani, G. Tiana, N. V. Dokholyan, S. Zapperi, C. A. M. La Porta, Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins , Sci. Rep.  9 , 7615 (2019)  [link]
  23. G. Franco, M. Cagiada, G. Bussi and G. Tiana, Statistical mechanical properties of sequence space determine the efficiency of the various algorithms to predict interaction energies and native contacts from protein coevolution , Phys. Biol.  16 , 046007 (2019)  [link]
  24. F. Vasile, M. Padigada, A. Siccardi, D. Potenza, G. Tiana, A combined NMR-computational study of the interaction between influenza-virus Hemagglutinin and sialic derivatives from human and avian receptors on the surface of transfected cells , Int. J. Mol. Sci.  19 , 1267 (2018)  [link]
  25. A. Possenti, M. Vendruscolo, C. Camilloni, G. Tiana, A method for partitioning the information contained in a protein sequence between its structure and function , Proteins  86 , 956-964 (2018)  [link]
  26. R. Capelli, G. Tiana and C. Camilloni, An implementation of the maximum-caliber principle by replica-averaged time-resolved restrained simulations , J. Chem. Phys.  148 , 184114 (2018)  [link]
  27. G. Tiana and L. Giorgetti, Integrating experiment, theory and simulation to determine the structure and dynamics of mammalian chromosomes , Curr. Opin. Struct. Biol.  49 , 11 (2018)  [link]
  28. M. Negri, M. Gherardi, G. Tiana, M. Cosentino Lagomarsino, Spontaneous domain formation in disordered copolymers as a mechanism for chromosome structuring , Soft Matter  14 , 6128 (2018)  [link]
  29. H. I. Rösner, M. Caldarini, A. Prestel, M. A. Vanoni, R. A. Broglia, A. Aliverti, G. Tiana and B. B. Kragelund, Cold denaturation of the HIV-1 protease monomer , Biochemistry  56 , 1029 (2017)  [link]
  30. S. A. Ghadami, F. Bemporad, B. M. Sala, G. Tiana, S. Ricagno and F. Chiti, FRET studies of the conformational states adopted by transthyretin for amyloid fibrl formation , Cell. Mol. Life Sci.  74 , 3577 (2017)  [link]
  31. F. Cola, F. Marchetti and G. Tiana, How likely are oscillations in a genetic feedback loop with delay? , Europ. Phys. J. E  40 , 74 (2017)  [link]
  32. Y. Zhan, L. Giorgetti and G. Tiana, Modelling Genome-wide Topological Associating Domains of Mouse Embryonic Stem Cells , Chromosome Res.  25 , 5 (2017)  [link]
  33. Y. Zhan, L. Mariani, I. Barozzi, E. G. Shultz, N. Bluthgen, M. Stadler, G. Tiana and L. Giorgetti, Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes , Genome Res.  27 , 479 (2017)  [link]
  34. R. Capelli, F. Marchetti, G. Tiana and G. Colombo, SAGE: a Fast Computational Tool for Linear Epitope Grafting onto a Foreign Protein Scaffold , J. Chem. Inf. Model.  57 , 6 (2017)  [link]
  35. R. Meloni and G. Tiana, Thermodynamic and Structural Effect of Urea and Guanidine Chloride on the Helical and on a Hairpin fragment of GB1 from Molecular Simulations , Proteins  85 , 753 (2017)  [link]
  36. R. Capelli, F. Villemont, E. Moroni, G. Tiana, A. van der Vaart and G. Colombo, Assessment of mutational effects on peptide stability through confinement simulations , J. Phys. Chem. Lett.  7 , 126 (2016)  [link]
  37. A. Sanzeni, V. Balasubramanian, G. Tiana and M. Vergassola, Complete coverage of space favors modularity of the grid system in the brain , Phys. Rev. E  94 , 062409 (2016)  [link]
  38. Y. Zhan, L. Giorgetti, G. Tiana, Looping probability of random heteropolymers helps to understand the scaling properties of biopolymers , Phys. Rev. E  94 , 032402 (2016)  [link]
  39. R. Meloni, C. Camilloni and G. Tiana, Properties of low-dimensional collective variables in the molecular dynamics of biopolymers , Phys. Rev. E  94 , 052406 (2016)  [link]
  40. G. Tiana, A. Amitai, T. Pollex, T. Piolot, D. Holcman, E. Heard, L. Giorgetti, Structural fluctuations of the chromatin fiber within topological associating domains , Biophys. J.  110 , 1234 (2016)  [link]
  41. A. Sanzeni, A. Celani, G. Tiana, M. Vergassola, Theory of feedback controlled brain stimulations for Parkinson’s disease , Physica A  441 , 121 (2016)  [link]
  42. F. Vasile, M. Civera, L. Belvisi, D. Potenza, G. Tiana, Thermodynamically-Weighted Conformational Ensemble of Cyclic RGD Peptidomimetics From NOE Data , J. Phys. Chem. B  120 , 7098 (2016)  [link]
  43. J. Marangon, M. S. Christodoulou, F. Casagrande, G. Tiana, L. Dalla Via, A. Aliverti, D. Passarella, G. Cappelletti, S. Ricagno, Tools for the rational design of bivalent microtubule-targeting drugs , Biochem. Biophys. Res. Comm.  479 , 48 (2016)  [link]
  44. A. Contini and G. Tiana, A many-body term improves the accuracy of effective potentials based on protein coevolutionary data , J. Chem. Phys.  143 , 025103 (2015)  [link]
  45. E. Molteni, G. Onida and G. Tiana, Conformational dependence of the circular-dichroism spectra of single amino acids from plane-waves-based density-functional theory calculations , J. Phys. Chem. B  119 , 4803 (2015)  [link]
  46. G. Tiana, Effect of disorder on the contact probability of elongated conformations of biopolymers , Phys. Rev. E  92 , 010702R (2015)  [link]
  47. G. Tiana, F. Villa, Y. Zhan, R. Capelli, C. Paissoni, P. Sormanni, E. Heard, L. Giorgetti, R. Meloni, MonteGrappa: an iterative Monte Carlo program to optimize biomolecular potentials in simplified models , Comp. Phys. Comm.  186 , 93 (2015)  [link]
  48. R. Capelli, C. Paissoni, P. Sormanni and G. Tiana, Iterative derivation of effective potentials to sample the conformational space of proteins at atomistic scale , J. Chem. Phys.  140 , 195101 (2014)  [link]
  49. L. Giorgetti, R. Galupa, E. P. Nora, T. Piolot, F. Lam, J. Dekker, G. Tiana and E. Heard, Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and trascription , Cell  157 , 950 (2014)  [link]
  50. R. Meloni, C. Camilloni and G. Tiana, Sampling the denatured state of polypeptides in water, urea and guanidine chloride to strict equilibrium conditions with the help of massively parallel computers , J. Chem. Theo. Comp.  10 , 846 (2014)  [link]
  51. M. Caldarini, P. Sonar, I. Valpapuram, D. Tavella, C. Volontè, V. Pandini, M. A. Vanoni, A. Aliverti, R. Broglia, G. Tiana and C. Cecconi, The complex folding behavior of HIV-1-protease monomer revealed by optical-tweezer single-molecule experiments and molecular-dynamics simulations , Biophys. Chem.  195 , 32 (2014)  [link]
  52. S. Kimura, M. Caldarini R. A. Broglia, N. Dokholyan and G. Tiana, The maturation of HIV-1 protease precursor studied by discrete molecular dynamics , Proteins  82 , 633 (2014)  [link]
  53. G. Tiana and M. H. Jensen, The dynamics of genetic control in the cell: the good and bad of being late , Philos. Trans. A  371 , 20120469 (2013)  [link]
  54. S. Lui and G. Tiana, The network of stabilizing contacts in proteins studied by coevolutionary data , J. Chem. Phys.  139 , 155103 (2013)  [link]
  55. P. Heidarsson, I. Calpapuram, C. Camilloni, A. Imparato, G. Tiana, F. Poulsen, B. Kragenlund, C. Cecconi, A Highly compliant protein native state with a spontaneous-like mechanical unfolding pathway , J. Am. Chem. Soc.  134 , 17068 (2012)  [link]
  56. G. Tiana and C. Camilloni, Ratcheted molecular-dynamics simulations identify efficiently the transition state of protein folding , J. Chem. Phys.  137 , 235101 (2012)  [link]
  57. S. Kimura, R. A. Broglia, G. Tiana, Thermodynamics of strongly allosteric inhibition , Europ. Biophys. J.  41 , 991 (2012)  [link]
  58. G. Tiana and L. Sutto, Equilibrium properties of realistic random heteropolymers and their relevance for globular and naturally unfolded proteins , Phys. Rev. E  84 , 061910 (2011)  [link]
  59. C. Camilloni, R.A. Broglia, G. Tiana, Hierarchy of folding and unfolding events of protein G, CI2, and ACBP from explicit-solvent simulations , J. Chem. Phys.  134 , 045105 (2011)  [link]
  60. M. Caldarini, L. Sutto, C. Camilloni, F. Vasile, R. A. Broglia and G. Tiana, Identification of the folding inhibitors of hen-egg lysozyme: gathering the right tools , Eur. Biophys. J.  39 , 911 (2010)  [link]
  61. L. Giorgetti, T. Siggers, G. Tiana, G. Caprara, S. Notarbartolo, T. Corona, M. Pasparakis, P. Milani, M. L. Bulyk, G. Natoli, Noncooperative Interactions between Transcription Factors and Clustered DNA Binding Sites Enable Graded Transcriptional Responses to Environmental Inputs , Molecular Cell  37 , 418 (2010)  [link]
  62. M. Caldarini, F. Vasile, D. Provasi, R. Longhi, G. Tiana, R. A. Broglia, Identification and characterization of folding inhibitors of hen egg lysozyme: an example of a new paradigm of drug design , Proteins  74 , 390 (2009)  [link]
  63. S. Ferramosca, M. Lo Cicero, A. E. Laface, F. Sirianni, E. Cesana, D. Provasi, G. Tiana, M. Galli, M. Moroni, A. Clivio, R. A. Broglia and S. Rusconi, In vitro efficacy of a non-conventional (folding) HIV-1 protease inhibitor without selection of resistance , Infection (abstract)  37 , 23 (2009)  [link]
  64. G. Tiana, Protein folding: Can high-performance computing improve our understanding? , Nuovo Cimento C 32  32 , 9 (2009)  [link]
  65. G. Tiana and R. A. Broglia, The molecular evolution of HIV-1 Protease simulated at atomic detail , Proteins  76 , 895 (2009)  [link]
  66. G. Verkhivker, G. Tiana, C. Camilloni, D. Provasi and R. A. Broglia, Atomistic Simulations of the HIV-1 Protease Folding Inhibition , Biophys J.  95 , 550 (2008)  [link]
  67. C. Camilloni, L. Sutto, D. Provasi, G. Tiana and R. A. Broglia, Early events in protein folding: Is there something more than hydrophobic burst? , Protein Science  17 , 1424 (2008)  [link]
  68. G. Tiana, Estimation of microscopic averages from metadynamics , Europ. Phys. J. B  63 , 235 (2008)  [link]
  69. C. Camilloni, D. Provasi, G. Tiana, R. A. Broglia, Exploring the Protein G Helix Free Energy Surface by Solute Tempering Metadynamics , Proteins  71 , 1647 (2008)  [link]
  70. R. A. Broglia, Y. Levy and G. Tiana, HIV-1 Protease folding and the design of drugs which do not create resistance , Curr. Opin. Struct. Biol.  18 , 60 (2008)  [link]
  71. F. Marini, C. Camilloni, D. Provasi, R. A. Broglia and G. Tiana, Metadynamic sampling of the free energy landscapes of proteins coupled with a Monte Carlo algorithm , Gene  422 , 37 (2008)  [link]
  72. A. Amatori, G. Tiana, J.Ferkinghoff-Borg and R. A. Broglia, The denatured state is critical in determining the properties of model proteins designed on different folds , Proteins  70 , 1047 (2008)  [link]
  73. S. Ferramosca, M. Lo Cicero, A. E. Laface, F. Sirianni, E. Cesana, D. Provasi, G. Tiana, M. Galli, M. Moroni, A. Clivio, R. A. Broglia and S. Rusconi, The non-conventional (folding) protease inhibitor blocks the human immunodeficiency virus type-1 replication without evidence of resistance during in vitro passage , Antiviral Therapy  13 , A34 (2008)  [link]
  74. C. Camilloni, A. Guerini Rocco, I. Eberini, E. Gianazza, R. A. Broglia, G. Tiana, Urea and guanidinium chloride denature Protein L in different ways in molecular dynamics simulations , Biophys. J.  94 , 4654 (2008)  [link]
  75. A. Podesta, G. Tiana, P. Milani and M. Manno, Early events in insulin fibrillization studied by time-lapse atomic force microscopy , Biophys. J.  90 , 589 (2007)  [link]
  76. M. Lo Cicero, A. E. Laface, S. Ferramosca, F. Sirianni, E. Cesana, D. Provasi, G. Tiana, M. Galli, M. Moroni, A. Clivio, R. A. Broglia and S. Rusconi, In vitro activity of a non-conventional (folding) protease inhibitor on human immunodeficiency virus type 1 replication , Antiviral Therapy  12 , S19 (2007)  [link]
  77. M. Bonomi, F. L. Gervasio, G. Tiana, D. Provasi, R. A. Broglia and M. Parrinello, Insight in the folding inhibition of the HIV–1 Protease by a small peptide , Biophys. J.  93 , 2813 (2007)  [link]
  78. M. Manno, E. F. Craparo, A. Podesta, D. Bulone, R. Carrotta, V. Martorana, G. Tiana and P. L. San Biagio, Kinetics of different processes in human insulin amyloid formation , J. Mol. Biol.  366 , 258 (2007)  [link]
  79. A. Broglia, G. Tiana, L. Sutto, D. Provasi, V. Perelli, Low-throughput model design of protein folding inhibitors , Proteins  67 , 469 (2007)  [link]
  80. C. Camilloni, D. Provasi, G. Tiana and R. A. Broglia, Optical absorption of a Green Fluorescent Protein variant: environment effects in a density functional study , J. Phys. Chem. B  111 , 10807 (2007)  [link]
  81. G. Tiana, S. Krishna, S. Pigolotti, M. H. Jensen and K. Sneppen, Oscillations and temporal signalling in cells , Physical Biology  4 , 1 (2007)  [link]
  82. G. Tiana, L. Sutto and R. A. Broglia, Use of the Metropolis algorithm to simulate the dynamics of protein chains , Physica A  380 , 241 (2007)  [link]
  83. R. A. Broglia, D. Provasi, F. Vasile , G. Ottolina, R. Longhi and G. Tiana, A folding inhibitor of the HIV-1 Protease , Proteins  62 , 928 (2006)  [link]
  84. L. Sutto, G. Tiana and R. A. Broglia, Sequence of events in folding mechanism: Beyond the Go model , Protein Sci.  15 , 1638 (2006)  [link]
  85. S. Colacino, G. Tiana and G. Colombo, Similar folds with different stabilization mechanisms: the cases of prion and doppel proteins , BMC Structural Biology  6 , 17 (2006)  [link]
  86. S. Colacino, G. Tiana, R. A. Broglia and G. Colombo, The Determinants of Stability in the Human Prion Protein: Insights into Folding and Misfolding from the Analysis of the Change in the Stabilization Energy Distribution in Different Conditions , Proteins  62 , 698 (2006)  [link]
  87. R. A. Broglia, G. Tiana, L. Sutto, D. Provasi, F. Simona, The physics of protein folding and of non-conventional drug design: Attacking AIDS with its own weapons , La Rivista del Nuovo Cimento  29 , 1 (2006)  [link]
  88. A. Amatori, J.Ferkinghoff-Borg, G. Tiana, R. A. Broglia, Thermodynamic features characterizing good and bad folding sequences obtained using a simplified off-lattice protein model , Phys. Rev. E  73 , 61905 (2006)  [link]
  89. G. Tiana, R. A. Broglia, L. Sutto and D. Provasi, Design of a folding inhibitor of the HIV-1 Protease , Mol. Simul.  31 , 765 (2005)  [link]
  90. A. Amatori, G. Tiana, L. Sutto, J.Ferkinghoff-Borg, A. Trovato and R. A. Broglia, Design of amino acid sequences to fold into C_alpha-model proteins , J. Chem. Phys.  123 , 54904 (2005)  [link]
  91. R. A. Broglia, G. Tiana, L. Sutto, D. Provasi and F. Simona, Design of HIV-1-PR inhibitors which do not create resistance: blocking the folding of single monomers , Protein Sci.  14 , 2668 (2005)  [link]
  92. I. Daidone, F. Simona, D. Roccatano, R.A. Broglia , G. Tiana, G. Colombo and A. Di Nola, Beta-hairpin conformation of fibrillogenic peptides: structure and alpha-beta transition mechanism revealed by molecular dynamics simulations , Proteins  57 , 198 (2004)  [link]
  93. G. Tiana, M. Colombo, D. Provasi, R. A. Broglia, Deriving amino acid contact potentials from their apparence frequencies in proteins: an inverse thermodynamical problem , J. Phys. Cond. Matt.  16 , 2551 (2004)  [link]
  94. G. Tiana, B. E. Shakhnovich, N. Dokholyan and E. I. Shakhnovich, Imprint of evolution on protein structures , Proc. Natl. Acad. Sci. USA  101 , 2846 (2004)  [link]
  95. F. Simona, G. Tiana, R. A. Broglia and G. Colombo, Modelling the alpha-helix to beta-hairpin transition mechanism and the formation of oligometric aggregates of the fibrillogenic peptide A-beta(12-28) , J. Mol. Graph. and Model.  23 , 263 (2004)  [link]
  96. G. Tiana, N. V. Dokholyan, R. A. Broglia and E. I. Shakhnovich, The evolution dynamics of model proteins , J. Chem. Phys.  121 , 2381 (2004)  [link]
  97. G. Tiana, F. Simona, R. A. Broglia and G. Colombo, Thermodynamics of beta-amyloid fibril formation , J. Chem. Phys.  120 , 8307 (2004)  [link]
  98. G. Tiana, F. Simona, G. M. S. De Mori, R. A. Broglia and G. Colombo, Understanding the determinants of stability and folding of small globular proteins from their energetics , Protein Sci.  13 , 113 (2004)  [link]
  99. R. A. Broglia, G. Tiana and R. Berera, Resistance proof, folding-inhibitor drugs , J. Chem. Phys.  118 , 4754 (2003)  [link]
  100. G. Tiana, D. Provasi and R. A. Broglia, Role of bulk and of interface contacts in the behaviour of model dimeric proteins , Phys. Rev. E  67 , 51909 (2003)  [link]
  101. M. H. Jensen, K. Sneppen and G. Tiana, Sustained oscillations and time delays in gene expression of protein Hes1 , FEBS Letters  531 , 176 (2003)  [link]
  102. G. Tiana and R. A. Broglia, Folding and design of dimeric proteins , Proteins  49 , 82 (2002)  [link]
  103. G. Tiana, M. H. Jensen and K. Sneppen, Time delay as a key to Apoptosis Induction in the p53 Network , Eur. Phys. J. B  29 , 135 (2002)  [link]
  104. G. Tiana, R. A. Broglia and D. Provasi, Designability of lattice model heteropolymers , Phys. Rev. E  64 , 11904 (2001)  [link]
  105. G. Tiana, R. A. Broglia and E. I. Shakhnovich, Energy Profile of the Space of Model Protein Sequences , J. Biol. Phys.  27 , 147 (2001)  [link]
  106. R. A. Broglia and G. Tiana, Hierarchy of Events in the folding of model proteins , J. Chem. Phys.  114 , 7267 (2001)  [link]
  107. J. Borg, M. H. Jensen, K. Sneppen and G. Tiana, Hydrogen bonds in polymer folding , Phys. Rev. Lett.  86 , 1031 (2001)  [link]
  108. A. Broglia and G. Tiana, Predicting the Three Dimensional Structure of a Lattice Designed Model Protein from its Primary Structure , J. Biol. Phys.  27 , 161 (2001)  [link]
  109. R. A. Broglia and G. Tiana, Reading the three–dimensional structure of a protein from its amino acid sequence , Proteins  45 , 421 (2001)  [link]
  110. G. Tiana and R. A. Broglia, Statistical Analysis of Native Contact Formation in the Folding of Designed Model Proteins , J. Chem. Phys.  114 , 2503 (2001)  [link]
  111. G. Tiana, R. A. Broglia and E. I. Shakhnovich, Hiking in the energy landscape in sequence space: a bumpy road to good folders , Proteins  39 , 244 (2000)  [link]
  112. R. A. Broglia, G. Tiana, H. E. Roman, E. Vigezzi and E. Shakhnovich, Stability of Designed Proteins against Mutations , Phys. Rev. Lett.  82 , 4727 (1999)  [link]
  113. R. A. Broglia, G. Tiana, S. Pasquali, H. E. Roman, E. Vigezzi, Folding and Aggregation of Designed Protein Chains , Proc. Natl. Acad. Sci. USA  95 , 12930 (1998)  [link]
  114. G. Tiana, R. A. Broglia, H. E. Roman, E. Vigezzi and E. Shakhnovich, Folding and Misfolding of Designed Protein-like Chains with Mutations , J. Chem. Phys.  108 , 757 (1998)  [link]
  115. M. Skorobogatiy and G. Tiana, Mapping of Mutation-sensitive Sites in Proteinlike Chains , Phys. Rev. E  58 , 3572 (1998)  [link]

Books and Book Chapters

  1. Y. Zhan, L. Giorgetti and G. Tiana, Polymer Folding Simulations from Hi-C Data , in Hi-C Data Analysis, Eds. F. Ferrari and S. Bicciato, Springer Methods ISBN 978-1-0716-1389-4 (2021)  [link]
  2. G. Tiana and L. Giorgetti, Coarse graining of a giant molecular system: the chromatin fiber , in Biomolecular Simulations, Methods and Protocols, Eds. C. Camilloni and M. Bonomi, Springer ISBN 978-1-4939-9608-7 (2019)  [link]
  3. G. Tiana and L. Giorgetti, Modelling the 3D conformations of genomes , Series in Computational Biopysics, Taylor and Francis Books, Inc. ISBN 9781138500792 (2018)  [link]
  4. G. Tiana, E. Heard and L. Giorgetti, From chromosome capture to polymer physics and back: investigating he three-dimensional structure of chromatin within topological associating domains , in Epigenetics and System Biology, Ed. L. Ringrose, Elsevier ISBN: 9780128030752 (2017)  [link]
  5. R. A. Broglia and G. Tiana, Protein Folding and Aggregation , Encyclopedia of Condensed Matter Physics, Eds. F. Bassani, J. Liedl and P. Wyder, Elsevier Press ISBN: 9780123694010 (2005)  [link]

Proceedings

  1. G. Tiana, S. Krishna, M. H. Jensen and K. Sneppen, Time oscillations in gene expression , Proceedings of the Geilo ASI School on ""Evolution from Cellular to Social Scales, eds. A.T. Skjeltorp and A.V. Belushkin, Kluwer Academic, Dordrecht, p. 61-81 (2008) 
  2. D. Provasi, G. Tiana and R. A. Broglia, Folding inhibition of HIV Protease: an experimental glance , p. 283-291, Proceedings of the CLXV course of the E. Fermi School on Protein Folding and Drug Design, Varenna (Italy), 4-14 July 2006, IOS Press (2007) 
  3. R. A. Broglia, G. Tiana,D. Provasi and L. Sutto, Molecular recognition through Local Elementary Structures: transferability of simple models to real proteins , p. 85-112, Proceedings of the CLXV course of the E. Fermi School on Protein Folding and Drug Design, Varenna (Italy), 4-14 July 2006, IOS Press (2007) 
  4. G. Tiana, D. Provasi, A. Amatori, L. Sutto and R. A. Broglia, Oligarchy in protein folding: the upper and lower classes in protein chains , p. 161-174, Proceedings of the CLXV course of the E. Fermi School on Protein Folding and Drug Design, Varenna (Italy), 4-14 July 2006, IOS Press (2007) 
  5. Stefano Rusconi, Mirko Lo Cicero, A. E. Laface, S. Ferramosca, E. Cesana, G. Tiana, D. Provasi, F. Sirianni, M. Galli, M. Moroni, A. Clivio, and R. A Broglia, Susceptibility to a NonConventional (Folding) Protease Inhibitor of Human Immunodeficiency Virus Type 1 Isolates In Vitro , p. 293-297, Proceedings of the CLXV course of the E. Fermi School on Protein Folding and Drug Design, Varenna (Italy), 4-14 July 2006, IOS Press (2007) 
  6. R. A. Broglia and G. Tiana, The physics of protein folding and drug design , p. 595-602, Proceedings of the 8th spring seminar on nuclear physics, Ed. A. Covello, Paestum, World Scientific (2005) 
  7. M.H. Jensen, K. Sneppen and G. Tiana, Oscillating Gene Expressions in Regulatory Networks , proceedings of the Geilo ASI School on "Forces, Growth and Form in Soft Condensed Matter: At the Interface between Physics and Biology", eds. A.T. Skjeltorp and A.V. Belushkin, Kluwer Academic, Dordrecht, p. 195-202 (2004) 
  8. R. A. Broglia and G. Tiana, Protein folding and non-conventional drug design: a primer for nuclear structure physicists , p. 117, Proceedings of the International Conference on Labirinth in Nuclear Structure, Crete, AIP Press (2004) 
  9. R. A. Broglia and G. Tiana, Physical Models for Protein Folding and Drug Design , p. 23-33, Proceedings Idea--Finding Symposium, Frankfurt Institite for Advanced Studies, Ep Systema, Hungary (2003) 
  10. R. A. Broglia and G. Tiana, From atomic nuclei to drug design , p. 419, Proceedings INFN workshop on Theoretical Nuclear and Many Body Systems, World Scientific (2002) 
  11. R. A. Broglia and G. Tiana, Complementary pictures for proteins: designability and foldability, are they equivalent? , p. 103-116, Proc. Int. School. Phys. E. Fermi, IOS Press (2001) 
  12. R. A. Broglia and G. Tiana, Mechanism of folding and aggregation of proteins , p. 69-98, Proc. Int. School. Phys. E. Fermi, IOS Press (2001) 
  13. R. A. Broglia and G. Tiana, The Protein Folding Problem , Theoretical Nuclear Physics in Italy, p. 157, Proc. of the VIIIth Conference on Problems in Theoretical Physics, Cortona, World Scientific (2001)