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Prof. Stefano Ricagno

We employ several structural biology techniques and many biophysical methods to characterise the structure, dynamics and fold stability of native and aggregated conformations.

Upcoming events

Protein misfolding and aggregation in disease
Mantova, February 12th-14th, 2025

Organizers: F. Chiti, M. Nuvolone, S. Ricagno.

Read our recent publications
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Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation
Broggini, L., Barzago, M. M., Speranzini, V., Schulte, T., Sonzini, F., Giono, M., ... & Ricagno, S. 

Journal of Molecular Biology 

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Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights
Frosio, A., Micaglio, E., Polsinelli, I., Calamaio, S., Melgari, D., Prevostini, R., ... & Rivolta, I. 

International Journal of Molecular Sciences

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The Cryo-EM Structure of Renal Amyloid Fibril Suggests Structurally Homogeneous Multiorgan Aggregation in AL Amyloidosis
Puri, S., Schulte, T., Chaves-Sanjuan, A., Mazzini, G., Caminito, S., Pappone, C., ... & Ricagno, S. 

Journal of Molecular Biology


Università degli Studi di Milano
  • Department of Biosciences
  • University of Milano
  • Via Celoria, 26. I-20133 Milano (Italy)
Policlinico San Donato
  • Institute of Molecular and Translational Cardiology
  • I.R.C.C.S. Policlinico S. Donato
  • Piazza Malan, 2. I-20097 San Donato Milanese (Italy)

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