Protein
Aggregation
Laboratory

Prof. Stefano Ricagno

We employ several structural biology techniques and many biophysical methods to characterise the structure, dynamics and fold stability of native and aggregated conformations.

From left to right: Melissa Milazzo (PhD St), Davide Pignatelli (junior researcher), Luca Broggini (Post-Doc), Cristina Visentin (Assistant professor), Federica Sonzini (junior researcher), Giulia Rizzi (PhD St), Stefano Ricagno (PI), Nour Al Hoda Kassab (M St), Riccardo Mattioli (B St).

Learn more about our research Meet the team

2025 events

Protein misfolding and aggregation in disease

Mantova, February 12th-14th, 2025

Organizers: F. Chiti, M. Nuvolone, S. Ricagno.

Conference page

PROTEAN Polymers of life: Proteins and Nucleaic Acids

Brescia, May 29th-30th, 2025

Organizers: E. Grillo, E. Cione, F. Cutruzzolà, R. Miggiano, S. Ricagno.

Conference page

Read our recent publications

The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light Chains

Puri S, Gadda A, Polsinelli I, Barzago MM, Toto A, Sriramoju MK, Visentin C, Broggini L, Valérie Bonnet DM, Russo R, Chaves-Sanjuan A, Merlini G, Nuvolone M, Palladini G, Gianni S, Hsu SD, Diomede L, Ricagno S.

Journal of Molecular Biology

A conformational fingerprint for amyloidogenic light chains

Paissoni C, Puri S, Broggini L, Sriramoju MK, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu SD, Ricagno S, Camilloni C.

Elife

Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions.

Visentin C, Rizzi G, Wen Y, Hotot M, Roy D, Gräslund T, Capelli R and
Ricagno S.

Biology Direct

Protein
Aggregation
Laboratory

2025 events

Protein misfolding and aggregation in disease

Mantova, February 12th-14th, 2025

PROTEAN Polymers of life: Proteins and Nucleaic Acids

Brescia, May 29th-30th, 2025

Read our recent publications

The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light Chains

Puri S, Gadda A, Polsinelli I, Barzago MM, Toto A, Sriramoju MK, Visentin C, Broggini L, Valérie Bonnet DM, Russo R, Chaves-Sanjuan A, Merlini G, Nuvolone M, Palladini G, Gianni S, Hsu SD, Diomede L, Ricagno S.

A conformational fingerprint for amyloidogenic light chains

Paissoni C, Puri S, Broggini L, Sriramoju MK, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu SD, Ricagno S, Camilloni C.

Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions.

Visentin C, Rizzi G, Wen Y, Hotot M, Roy D, Gräslund T, Capelli R and
Ricagno S.

Contacts

Phone

Email

ORCID

Research Gate

Università degli Studi di Milano

ProteinAggregationLaboratory

2025 events

Protein misfolding and aggregation in disease

Mantova, February 12th-14th, 2025

PROTEAN Polymers of life: Proteins and Nucleaic Acids

Brescia, May 29th-30th, 2025

Read our recent publications

The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light Chains

Puri S, Gadda A, Polsinelli I, Barzago MM, Toto A, Sriramoju MK, Visentin C, Broggini L, Valérie Bonnet DM, Russo R, Chaves-Sanjuan A, Merlini G, Nuvolone M, Palladini G, Gianni S, Hsu SD, Diomede L, Ricagno S.

A conformational fingerprint for amyloidogenic light chains

Paissoni C, Puri S, Broggini L, Sriramoju MK, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu SD, Ricagno S, Camilloni C.

Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions.

Visentin C, Rizzi G, Wen Y, Hotot M, Roy D, Gräslund T, Capelli R andRicagno S.

Contacts

Phone

Email

ORCID

Research Gate

Università degli Studi di Milano

Protein
Aggregation
Laboratory

Visentin C, Rizzi G, Wen Y, Hotot M, Roy D, Gräslund T, Capelli R and
Ricagno S.