SFRBM Pre-Meeting Workshop

Wednesday, November 14, 2018   |  Pre-Meeting Workshop – Half Day

1:00 pm – 3:30 pm




Chairs:  Henry Jay Forman, PhD, University of Southern California; University of California, Merced, USA;  Corinne Spickett, MA, DPhil, Aston University, Birmingham, UK



Lipid oxidation generates numerous bioactive products, which can act as either signaling molecules involved in cell growth regulation, and stimulants of increased antioxidant defense, or signal for and participate in cell death. Hence, various acute and chronic human diseases metabolic, degenerative, inflammatory and malignant are associated with lipid oxidation. Therefore, this workshop will give an updated overview on methods in lipid oxidation research that might clarify the most relevant aspects of lipid oxidation and support its positioning within the interdisciplinarity of free radical biology and medicine.

13:00 – 13:10      Welcome

13:10  – 13:40     MS-based identification of covalent adducts in oxidize LDL                                      

                             Koji Uchida, Ph.D., The University of Tokyo, Japan

13:40  – 14:10     Methods to measure isolevuglandin protein and phospholipid adducts

                             Sean Davies, Ph.D., Vanderbilt University, Nashville, USA

14:10  – 14:25     Break     

14:25 – 14:55     Immunochemical findings of HNE-His adducts in human diseases

                            Neven Zarkovic, M.D.,Ph.D., LabOS, Rudjer Boskovic Institute, Zagreb, Croatia

14:55 – 15:25     Nitro-fatty acids: detection, electrophilic signaling and therapeutics

                            Homero Rubbo, Ph.D., Universidad de la Republica, Montevideo, Uruguay

15:25 – 15:30    Summary