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Research

The Sattin Group applies organic chemistry to chemical biology problems and molecular recognition events.

When probed and analysed in enough detail molecular recognition events allow a deeper understanding of many biological processes in both physiological and pathological conditions.

Our group is focused on the design and synthesis of small molecules tailored to interact with specific protein targets.

In particular, we are currently working on the inhibition of a survival bacterial enzyme to hamper bacterial persistence, the allosteric regulation of the chaperone protein Hsp90 and the modulation of self and non-self recognition via protein-carbohydrate interactions.

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