Publications

39.

Tumor Carbohydrate Associated Antigen Analogs as Potential Binders for Siglec-7

Di Carluccio, C.; Milanesi, F.; Civera, M.; Abreu, C.; Sattin, S.; Francesconi, O.; Molinaro, A.; Vaněk, O.; Marchetti, R.; Silipo, A.

Eur. J. Org. Chem., 2023

38.

Nature-inspired and medicinally relevant short peptides

Ciulla, M.G.; Civera, M.; Sattin, S.; Kumar, K.

Explor Drug Sci. 2023, 1, 140–171

37.

Novel self-assembling cyclic peptides with reversible supramolecular nanostructures

Ciulla, M.G.; Fontana, F.; Lorenzi, R.; Marchini, A.; Campone, L.; Sadeghi, E.; Paleari, A.; Sattin, S.; Gelain, F.

Mat. Chem. Front., 2023

36.

New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds

Coppa, C.; Sorrentino, L.; Civera, M.; Minneci, M.; Vasile, F.; Sattin, S.

Molecules, 2022, 27 (10), 3097

Special Issue Women in Bioorganic Chemistry

35.

Conformationally Constrained Sialyl Analogues as New Potential Binders of h-CD22

Forgione, R.E.; Nieto, F.F.; Di Carluccio, C.; Milanesi, F.; Fruscella, M.; Papi, F.; Nativi, C.; Molinaro, A.; Palladino, P.; Scarano, S.; Minunni, M.; Montefiori, M.; Civera, M.; Sattin, S.; Francesconi, O.; Marchetti, R.; Silipo, A.

ChemBioChem, 2022, 23 (10), e202200076

34.

Analysis of Hsp90 allosteric modulators interactome reveals a potential dual action mode involving mitochondrial MDH2

Cassiano, C.; Morretta, E.; Costantini, M.; Fassi, E.M.A.; Colombo, G.; Sattin, S.; Casapullo, A.

Bioorganic Chem., 2021, 115, 105258

33.

Chemical and Biophysical Approaches to Allosteric Modulation

Civera, M.; Moroni, E.; Sorrentino, L.; Vasile, F.; Sattin, S.

Eur. J. Org. Chem., 2021, 30, 4245-4259

Dedicated to Franco Cozzi’s 70th Birthday

Collection YourJOC Talents

The paper was highlighted in the Front Cover

32.

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

Thepaut, M.; Luczkowiak, J.; Vives, C.; Labiod, N.; Bally, I.; Lasala, F.; Grimoire, Y.; Fenel, D.; Sattin, S.; Thielens, N.; Schoehn, G.; Bernardi, A.; Delgado, R.; Fieschi, F.

PLoS Pathog., 2021, 17(5), e1009576

31.

Homology Model of a Catalytically Competent Bifunctional Rel Protein

Civera, M.; Sattin, S.

Front. Mol. Biosci., 2021, 8, 628596

30.

Behavior of glycolylated sialoglycans in the binding pockets of murine and human CD22

Di Carluccio, C.; Forgione, R.E.; Montefiori, M.; Civera, M.; Sattin, S.; Smaldone, G.; Fukase, K.; Manabe, Y.; Crocker, P.R.; Molinaro, A.; Marchetti, R.; Silipo, A.

iScience, 2021, 24(1), 101998

29.

When the Others Become Us: A Chemist’s Perspective of the COVID-19 Outbreak in Italy

Laura Kiessling, Christina MacLaughlin, and Sara Sattin

ACS Chem. Biol. 2020, 15, 6, 1279–1281

28.

Interfering with the Sugar Code: Ten Years Later

Prof. Anna Bernardi, Prof. Sara Sattin

Eur. J. Org. Chem., 2020, https://doi.org/10.1002/ejoc.202000155

27.

Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis

Medve, L.; Achilli, S.; Guzman-Caldentey, J.; Thepaut, M.; Senaldi, L.; Le Roy, A.; Sattin, S.; Ebel, C.; Vives, C.; Martin-Santamaria, S.; Bernardi, A.; Fieschi, F.

Chem. Eur. J. 2019, 25 (64), 14659-14668.

26.

Optimised Synthesis of the Bacterial Magic Spot (p)ppGpp Chemosensor PyDPA

Conti, G.; Minneci, M.; Sattin, S.

ChemBioChem 2019, 20, 1717-1721.

25.

Facile access to pseudo-thio-1,2-dimannoside, a new glycomimetic DC-SIGN antagonist

Sattin, S.; Vives, C.; Colombo, C.; Fieschi, F.; Bernardi, A.

Bioorg Med Chem 2017, 25 (19), 5142-5147.

24.

The small RNA ReaL: a novel regulatory element embedded in the Pseudomonas aeruginosa quorum sensing networks

S. Carloni; R. Macchi; S. Sattin; S. Ferrara; G. Bertoni

Environ Microbiol 2017, 19, 4220

23.

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

M. Bagdany; G. Veit; R. Fukuda; R. G. Avramescu; T. Okiyoneda; I. Baaklini; J. Singh; G. Sovak; H. Xu; P. M. Apaja; S. Sattin; L. K. Beitel; A. Roldan; G. Colombo; W. Balch; J. C. Young; G. L. Lukacs

Nature communications 2017, 8, 398

22.

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads

I. D’Annessa, S. Sattin, J. Tao, M. Pennati, C. Sànchez-Martìn, E. Moroni, A. Rasola, N. Zaffaroni, D.A. Agard, A. Bernardi, and G. Colombo

Chem. Eur. J. 2017, 23, 5188

21.

Stereoselective innovative synthesis and biological evaluation of new real carba analogues of minimal epitope Manα(1,2)Man as DC-SIGN inhibitors

V. Bordoni; V. Porkolab; S. Sattin; M. Thépaut; I. Frau; L. Favero; P. Crotti; A. Bernardi; F. Fieschi; V. Di Bussolo

RSC Adv. 2016, 6, 89578

20.

Linear biocompatible glyco-polyamidoamines as dual action mode virus infection inhibitors with potential as broad-spectrum microbicides for sexually transmitted diseases

N. Mauro; P. Ferruti; E. Ranucci; A. Manfredi; A. Berzi; M. Clerici; V. Cagno; D. Lembo; A. Palmioli; S. Sattin

Sci. Rep. 2016, 6, 33393

19.

Synthesis of functionalized 2-(4-hydroxyphenyl)-3-methylbenzofuran allosteric modulators of Hsp90 activity

Sattin;* M. Panza; F. Vasile; F. Berni; G. Goti; J. Tao; D. Agard; G. Colombo; A. Bernardi

Eur J Org Chem 2016, 2016, 3349

18.

Molecular Dynamics Simulations Reveal the Mechanisms of Allosteric Activation of Hsp90 by Designed Ligands

E. Moroni; S. Sattin; J. Tao; D. A. Agard; A. Bernardi; G. Colombo

Sci Rep 2016, 6, 23830

17.

Glycoconjugates and Glycomimetics as Microbial Anti-Adhesives

Sattin; A. Bernardi

Trends Biotechnol. 2016, 34, 483

16.

Design and synthesis of glycomimetics

Sattin; A. Bernardi

In Carbohydrate Chemistry: Volume 41; The Royal Society of Chemistry: 2016; Vol. 41, p 1

15.

Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering

Guzzi; P. Alfarano; I. Sutkeviciute; S. Sattin; R. Ribeiro-Viana; F. Fieschi; A. Bernardi; J. Weiser; J. Rojo; J. Angulo; P. M. Nieto

Org Biomol Chem 2016, 14, 335

14.

Scaffold Optimisation of Tetravalent Antagonists of the Mannose Binding Lectin

Goti; A. Palmioli; M. Stravalaci; S. Sattin; M. G. De Simoni; M. Gobbi; A. Bernardi
Chem. Eur. J. 2016, 22, 3686

Chem. Eur. J. 2016, 22, 3686

13.

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands

Sattin; J. Tao; G. Vettoretti; E. Moroni; M. Pennati; A. Lopergolo; L. Morelli; A. Bugatti; A. Zuehlke; M. Moses; T. Prince; T. Kijima; K. Beebe; M. Rusnati; L. Neckers; N. Zaffaroni; D. A. Agard; A. Bernardi; G. Colombo

Chem. Eur. J. 2015, 21, 13598 highlighted as Very Important Paper

12.

DC-SIGN as a Target for Drug Development Based on Carbohydrates

Sattin; F. Fieschi; A. Bernardi

In Carbohydrate Chemistry: State of the Art and Challenges for Drug Development; IMPERIAL COLLEGE PRESS: 2015, p 379

11.

Carbohydrates: A phenol sandwich fights diabetes

Bernardi; S. Sattin

Nat Chem Biol 2015, 11, 635

10.

Unique DC-SIGN clustering activity of a small glycomimetic: A lesson for ligand design

Sutkeviciute; M. Thepaut; S. Sattin; A. Berzi; J. McGeagh; S. Grudinin; J. Weiser; A. Le Roy; J. J. Reina; J. Rojo; M. Clerici; A. Bernardi; C. Ebel; F. Fieschi

ACS Chem Biol 2014, 9, 1377

9.

Synthesis of potential allosteric modulators of Hsp90 by chemical glycosylation of Eupomatenoid-6

Morelli; A. Bernardi; S. Sattin*

Carbohydr Res 2014, 390C, 33

8.

Pseudo -Mannosylated DC-SIGN Ligands as Potential Adjuvants for HIV Vaccines

Berzi; N. Varga; S. Sattin; P. Antonazzo; M. Biasin; I. Cetin; D. Trabattoni; A. Bernardi; M. Clerici

Viruses 2014, 6, 391

7.

Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design

Thepaut; C. Guzzi; I. Sutkeviciute; S. Sattin; R. Ribeiro-Viana; N. Varga; E. Chabrol; J. Rojo; A. Bernardi; J. Angulo; P. M. Nieto; F. Fieschi

J Am Chem Soc 2013, 135, 2518

6.

Giant regular polyhedra from calixarene carboxylates and uranyl

Sattin; S. Pasquale; E. C. Escudero-Adan; M. Martinez-Belmonte; J. de Mendoza

Nat. Commun. 2012, 3, 785 highlighted in ChemistryViews

5.

Design , synthesis and activity evaluation of mannose-based DC-SIGN antagonists

Obermajer; S. Sattin; C. Colombo; M. Bruno; U. Švajger; M. Anderluh; A. Bernardi

Mol Divers 2011, 15, 347

4.

Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection

Luczkowiak; S. Sattin; I. Sutkeviciute; J. J. Reina; M. Sanchez-Navarro; M. Thepaut; L. Martinez-Prats; A. Daghetti; F. Fieschi; R. Delgado; A. Bernardi; J. Rojo

Bioconjugate Chem. 2011, 22, 1354

3.

Inhibition of DC-SIGN-mediated HIV infection by a linear trimannoside mimic in a tetravalent presentation

Daghetti; M. Thepaut; A. Berzi; M. Sanchez-Navarro; G. Tabarani; J. Rojo; F. Fieschi; M. Clerici; A. Bernardi

ACS Chem. Biol. 2010, 5, 301

2.

An assay for functional dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) inhibitors of human dendritic cell adhesion

Obermajer; U. Svajger; M. Jeras; S. Sattin; A. Bernardi; M. Anderluh

Anal. Biochem. 2010, 406, 222

1.

Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity

J. Reina; S. Sattin; D. Invernizzi; S. Mari; L. Martinez-Prats; G. Tabarani; F. Fieschi; R. Delgado; P. M. Nieto; J. Rojo; A. Bernardi

ChemMedChem 2007, 2, 1030