Recent Publications

Rotational Motion in Bispidines: A Conformational Study

Organic Letters 2025, DOI: 10.1021/acs.orglett.5c02839

Francesco Migliano, Luca Pozzi, Andrea Citarella, Giovanni Macetti, Leonardo Lo Presti, Daniele Passarella* and Valerio Fasano*

Asymmetric Total Synthesis of (−)‐Glycybridin B, a Pharmacophore Screened Candidate for Tubulin Binding in Chemistry – A European Journal has the following publication status: Published Online

Chemistry – A European Journal 2025, DOI: 10.1002/chem.202502228

Alice Maiocchi, Maxim Shevelev, Zlata Boiarska, Juan Estévez-Gallego, Francesca Bonato, Paolo Orlando, Alessandra Chinosi, Emanuele Marcone, Andrea Citarella, Dragos Horvath, Michel O. Steinmetz, Andrea E. Prota, Alexandre Varnek, Valerio Fasano and Daniele Passarella

Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer

Journal of Medicinal Chemistry 2025, DOI: 10.1021/acs.jmedchem.5c00717

Andrea Citarella, Silvia Belluti, Davide Bonanni, Davide Moi, Isabella Piccinini, Arianna Rinaldi, Chiara Papulino, Rosaria Benedetti, Laura Cuoghi, Stefano Di Ciolo, Alessandra Silvani, Lucia Altucci, Luca Pinzi, Silvia Franchini, Daniele Passarella, Claudia Sorbi, Clelia Giannini, Carol Imbriano, Giulio Rastelli

Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity

Bioorganic and Medicinal Chemistry 2025, DOI: 10.1016/j.bmc.2025.118258

Andrea Citarella, Giulia Sibille, Davide Moi, Alessandro Dimasi, Tommaso Braga, Lorenzo Dal Col, Lorenzo Ruberto, Stefano Pieraccini, Maurizio Sironi, Nicola Micale, Tanja Schirmeister, Valerio Fasano, Alessandra Silvani, Clelia Giannini, Giorgio Gribaudo, Daniele Passarella

Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats

European Journal of Medicinal Chemistry, 2025, 293, 117736, DOI: 10.1016/j.ejmech.2025.117736

Alice Maiocchi, Martina Pedrini, Veronica Ferrari, Agata Sofia Assunçao Carreira, Vincenzo Maria D’Amore, Federica Santoro, Anna Di Porzio, Maddalena Bosetti, Riccardo Cristofani, Alessandra Silvani, Diego Brancaccio, Luciana Marinelli, Francesco Saverio Di Leva, Alessandro Provenzani, Angelo Poletti, Pierfausto Seneci

Automated fluorine-18 radiolabeling via an alkyne–azide cycloaddition reaction on a dual peptide-functionalized liposome surface for in vivo PET imaging

Frontiers in Pharmacology, 2025, 16, 1–16. DOI: 10.3389/fphar.2025.1566257

Marco Iannone, Marcelo Kravicz, Paolo Rainone, Antonia I. Antoniou, Stefano Stucchi, Silvia Valtorta, Arianna Amenta, Elia Anna Turolla, Sara Pellegrino, Daniele Passarella, Elisa Vino, Sergio Todde, Francesca Re, Pierfausto Seneci, Rosa Maria Moresco

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity

Pharmaceutics 2025, 17(5), 636; DOI: 10.3390/pharmaceutics17050636

Arianna Amenta, Giulia Nordio, Francesco Piazzola, Maria Luisa Di Paolo, Fabio Milani, Martina Giacomini,
Andrea Citarella,* Umberto Ciriello, Giuseppe Paladino, Sara Pellegrino, Federica Silvestri, Valerio Fasano,
Lisa Dalla Via* e Daniele Passarella

Access to Highly Functional and Polymerizable Carbonate-Drug Conjugates

ChemSusChem 2025, DOI: 10.1002/cssc.202500031

Wangyu Shi, Thirusangumurugan Senthamarai, Matteo Lanzi, Paolo Orlando, Rodrigo Nogués Martín, Arjan W. Kleij

Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks

Bioorganic & Medicinal Chemistry 2025, DOI: 10.1016/j.bmc.2025.118124

Martina Pedrini †, Luca Pozzi †, Francesca Sacchi, Andrea Citarella*, Valerio Fasano, Pierfausto Seneci, Stefano Pieraccini, Lorenzo Ruberto, Helena Perez Peña, Alfredo Garzino-Demo, Adriana Vitiello, Leonardo Sernicola, Alessandra Borsetti, Arianna Calistri, Cristina Parolin and Daniele Passarella*