APIS group

Amino acids, Peptidomimetics, peptides, protein InteractionS group

application

application / unnatural amino acid

Dipeptide Nanotubes Containing Unnatural Fluorine-Substituted β2,3-Diarylamino Acid and L‑Alanine as Candidates for Biomedical Applications

 The synthesis and the structural characterization of dipeptides composed of unnatural fluorine-substituted β2,3-diarylamino acid and L-alanine are reported. Depending on the stereochemistry of the β amino acid, these dipeptides are able to self-assemble into proteolytic stable nanotubes....

application

Promising antiproliferative platinum(II) complexes based on imidazole moiety: synthesis, evaluation in HCT-116 cancer cell line and interaction with Ctr-1 Met-rich domain

  Promising antiproliferative platinum(II) complexes based on imidazole moiety: synthesis, evaluation in HCT-116 cancer cell line and interaction with Ctr-1 Met-rich domain doi:10.1016/j.bmc.2015.03.044 A series of imidazole based platinum(II) complexes were synthesised and evaluated...