PhD Student: Luca De Vincenti
Tutors: Prof. Francesca Cappitelli, Dr. Fabio Forlani – DeFENS
Dean: Prof. Francesco Bonomi
Research area: Agri-Environment
PhD title achieved on: 18th December 2018
Plant-derived compounds as antibiofilm agents
The principal aim of this PhD project is to unravel the effects of bioactive-enriched fractions obtained from halophytes and nanoparticles (NPs) for the development of innovative biocide-free, eco-sustainable strategies to counteract unwanted biofilms. Using sub-lethal doses of bio-inspired molecules and NPs we offer an elegant way to interfere with specific key-steps that orchestrate biofilm formation, disarming microorganisms without affecting their existence, sidestepping drug resistance and extending the efficacy of the current arsenal of antimicrobial agents.
biofilms, plant-derived compounds, sub-lethal concentrations, biocide-free strategies, oxidative stress, nanoparticles
DeFENS – Department of Food, Environmental and Nutritional Sciences
Faculty of Agricultural and Food Sciences
Università degli Studi di Milano
Via Celoria 2 – 20133 Milano – Italy
Phone: +39(2) 503.19146
Prof. Dr. Jutta Papenbrock, Institute of Botany, Leibniz University of Hannover, Hannover (Germany)
Fellowship sponsor: Università degli Studi di Milano
De Vincenti L., Cattò C., Borgonovo G., Bassoli A., Saracchi M., Villa F., Cappitelli F. “Evaluation of antibiofilm property of Perilla frutescens essential oils against plant pathogenic fungi”. Abstract submitted for poster session at IV International Conference on Antimicrobial Research – ICAR2016, 29 June-1 July 2016, Torremolinos-Malaga (Spain).
Garuglieri E., Zanchi R., Cattò C., Troiano F., De Vincenti L., Cappitelli F. “Unraveling the effects of food-related engineered NANOparticles on the GUT interactive ecosystem (NanoGut)” – MD-2015 Microbial diversity: the challenge of complexity, Congress of Società Italiana di Microbiologia Agraria, Alimentare e Ambientale (SIMTREA), Perugia (Italy), 27th-29th October 2015.