PhD Student: Anđela Martinović (ORCID n. 0000-0001-5972-6701)
Tutor: Prof. Diego Mora, DeFENS, University of Milano
Dean: Prof. Diego Mora
Research area: Food Science and Nutrition
Probiotics and Food associated microorganisms: ecology, molecular and functional characterization, impact on host health
The general benefit of probiotics on gut microbiota derives from creating a more favorable gut environment, through mechanisms shared by most probiotics. To this aim the survival through the human gastro-intestinal tract is considered one of the key points of probiotic biomasses. Production process parameters, post-fermentation treatments and cryoprotectants have been widely investigated to access their relevance on microbial biomasses viability and survival, but their role in the robustness of probiotic during the transit along the gastro-intestinal tract was rarely addressed. Therefore, the main goal of my PhD research is the optimization of the fermentation and post-fermentation processes for probiotics production in order to implement their stability and their fitness during the gastro-intestinal tract transit in human subjects.
probiotic, fermentation, viability, recovery
Ufficio Dottorandi 3° piano (DeFENS) – Università degli Studi di Milano, Via Mangiagalli, 25 – 20133, Milano, Italy, phone +3902 50319237, mail: email@example.com
Inés Martínez, Sacco SRL, Via Alessandro Manzoni, 29/A, 22071 Cadorago CO
Fabio Dal Bello, Sacco SRL, Via Alessandro Manzoni, 29/A, 22071 Cadorago CO
Fellowship sponsor: Università degli Studi di Milano
Papers with impact factor
Martinović, A., Cocuzzi, R., Arioli, S., & Mora, D. (2020). Streptococcus thermophilus: To Survive, or Not to Survive the Gastrointestinal Tract, That Is the Question!. Nutrients, 12(8), 2175. doi: 10.3390/nu12082175
Di Cagno, R., Filannino, P., Cantatore, V., Polo, A., Celano, G., Martinovic, A., Cavoski, I., & Gobbetti, M. (2020). Design of potential probiotic yeast starters tailored for making a cornelian cherry (Cornus mas L.) functional beverage. International Journal of Food Microbiology, 108591. doi: 10.1016/j.ijfoodmicro.2020.108591
Martinović, A., & Cavoski, I. (2020). The exploitation of cornelian cherry (Cornus mas L.) cultivars and genotypes from Montenegro as a source of natural bioactive compounds. Food Chemistry, 126549. doi: 10.1016/j.foodchem.2020.126549
Martinović, A., Arioli, S., Filardi, R., Cocuzzi, R., & Mora, D. Development of a Strain-Specific qPCR Protocol for the Detection and Quantification of a Probiotic S. thermophilus in Fecal Samples. 14th International Scientific Conference On Probiotics, Prebiotics, Gut Microbiota And Health (IPC)” Prague (Czech Republic), 11 November 2020.
Filardi, R., Martinović, A., Cocuzzi, R., Mora, D., & Arioli, S. Mucin-Dependent Polymorphism of a Growing Culture of Akkermansia muciniphila DSM 22959 Revealed by Flow Cytometry. 14th International Scientific Conference On Probiotics, Prebiotics, Gut Microbiota And Health (IPC)” Prague (Czech Republic), 11 November 2020.
Martinović, A., Sourabie, S.A, Arioli, S., & Mora, D. Optimization of Culture Conditions for Probiotic L. Acidophilus LA03 Biomass Production: From Microplates to Lab-Scale Bioreactor. 13th Symposium on Lactic Acid Bacteria, online event, 23-26 August 2021.
Martinović, A., Cocuzzi, R., Arioli, S., & Mora, D. Development of a Strain-Specific qPCR Protocol for the Detection and Quantification of a Probiotic S. thermophilus BT01 in Fecal Samples. 13th Symposium on Lactic Acid Bacteria, online event, 23-26 August 2021.
Martinović, A. Effect of fermentation and post-fermentation parameters on the viability, robustness and probiotic traits of lactic acid bacteria and bifidobacteria. The first (XXV) Workshop on the developments in the Italian Phd research on food science technology and biotechnology, 14-15 September 2021.
BSc in Food technology, University of Donja Gorica, Podgorica, Montenegro
Thesis title: Quality parameters of red wine Vranac in the wine district of Podgorica
Specialization in Food technology of plant food origin, University of Donja Gorica, Podgorica, Montenegro
Thesis title: Impact of freezing process on antioxidative potential and comparative analysis of berry fruits from the territory of Montenegro
MSc in Organic agriculture, Mediterranean Agronomic Institute of Bari (CIHEAM), Bari, Italy
Thesis title: Novel organic fermented cornelian cherry smoothie as a potential probiotic beverage