PhD student profile, Claudia Capusoni

PhD Student: Claudia Capusoni

Tutor: Prof. Concetta Compagno

Dean: Prof. Ella Pagliarini

Research area: Chemistry and Biochemistry & Food Science and Nutrition

 

Research topic

Biotechnological processes for the transformation of agri-food residues into value-added molecules

 

Project Synopsis

The aim of my PhD project is to characterize a group of “non conventional yeasts” with food-industrial properties in order to develop the most promising strains into a “cell-factory”.

Our attention will be first focus on environmental yeast species among which marine yeasts and yeasts isolated from food matrix. During the second part of my project I plan to set up methods in order to obtain interesting molecules to be employed as dietary supplement in the production of functional foods and feeds.

 

Project keywords

non conventional yeast, cell factory, value added molecules, dietary supplements

 

Contacts

Via Mangiagalli 25, terzo piano lab 3074

20133 Milano

claudia.capusoni@unimi.it

 

Collaborations

Dr. Stefania Arioli

Prof. Francesco Molinari

 

Sponsor

Fellowship sponsor: Università degli Studi di Milano

 

Publications

Publications with impact factor

Donzella S. , Cucchetti D., Capusoni C., Rizzi A., Galafassi S., Gambaro C. and Compagno C. (2019). Engineering cytoplasmic acetyl-CoA synthesis decouples lipid production from nitrogen starvation in the oleaginous yeast Rhodosporidium azoricum. Microbial Cell Factories.18:199

Serra I., Capusoni C., Molinari, F., Musso L., Pellegrino L., Compagno, C.(2019). Marine Microorganisms for Biocatalysis: Selective Hydrolysis of Nitriles with a Salt-Resistant Strain of Meyerozyma guilliermondii. Marine Biotechnology. 21(2), pp. 229-239

Capusoni C., Arioli S., Donzella S., Guidi B., Serra I., Compagno C.(2019). Hyper-Osmotic Stress Elicits Membrane Depolarization and Decreased Permeability in Halotolerant Marine Debaryomyces hansenii Strains and in Saccharomyces cerevisiae. Front. Microbiol., 82(15):4673-4681.

Capusoni, C., Rodighiero, V. ,Cucchetti, D. ,Galafassi, S.,Bianchi, D. ,Franzosi, G.,Compagno C.(2017). Characterization of lipid accumulation and lipidome analysis in the oleaginous yeasts Rhodosporidium azoricum and Trichosporon oleaginosus, Bioresource Technology. 238: 281-289.

Capusoni C., Arioli S.,  Zambelli P., Moktaduzzaman M., Mora D.,  Compagno C.(2016). Effects of oxygen availability on acetic acid tolerance and intracellular pH in Dekkera bruxellensis. Appl. Environ. Microbiol.  82(15):4673-4681

Nicastro R., Tripodi F.,  Guzzi C., Reghellin V., Khoomrung S, Capusoni C., Compagno C., Airoldi C , Nielsen J., Alberghina L.,  Coccetti.P. (2015).Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK. BBA Molecular Cell Research. (2015) 1853(7):1615-1625.

Moktaduzzaman M., Galafassi S., Capusoni C., Vigentini I.,  Ling Z.,Piskur J.  and Compagno C.(2015). Galactose utilization sheds new light on sugar metabolism in the sequenced strain Dekkera bruxellensis CBS 2499. FEMS Yeast Research. 15(2):1–9

Galafassi S., Capusoni C., Moktaduzzaman Md, Compagno C.(2013). Utilization of nitrate abolishes the ‘‘Custers effect’’ in Dekkera bruxellensis and determines a different pattern of fermentation products. J Ind Microbiol Biotechnol.) 40:297–303.

 

Posters

Capusoni C. Application of not conventional yeasts in food related bioprocesses. XXIV Workshop on the Developments in the Italian PhD Research on Food Science Technology and Biotechnology. Florence, Italy, September 2019.

Capusoni C., Arioli S., Donzella S.,  Guidi B., Serra I., Compagno C. Hyper-Osmotic Stress Elicits Membrane Depolarization and Decreased Permeability in Halotolerant Marine Debaryomyces hansenii Strains and in Saccharomyces cerevisiae. 7^th Conference on Physiology of Yeast & Folamentous Fungi (PYFF). Milan, Italy. June 2019

Serra I, Capusoni C., Compagno C. Marine halotolerance yeast for biocatalysis. 7^th Conference on Physiology of Yeast & Folamentous Fungi (PYFF). Milan, Italy. June 2019

Capusoni C. Marine yeasts as “Cell factory” for the production of value added molecules. XXIII Workshop on the Developments in the Italian PhD Research on Food Science Technology and Biotechnology. Oristano, Italy, September 2018.

 

Patents

IT102017000081383 Rodighero V., Franzosi G., Compagno C., Capusoni C. Variant oleaginous yeast and its use for the production of lipids

 

Others:

Tutoring activities

Giorgia Frabetti (matricola 880491 Bachelor degree in Biotechnology) AA 2018-2019 Relatore Concetta Compagno, Correlatore: Claudia Capusoni

Silvia Donzella (matricola 879551 Master degree in Molecular Biotechnology and Bioinformatics) AA 2016-2017 Relatore Concetta Compagno, Correlatore: Claudia Capusoni

Orlando Frallicciardi (matricola 805723 Master degree in Molecular Biotechnology and Bioinformatics) AA 2013-2014 Relatore Concetta Compagno, Correlatore: Claudia Capusoni

 

Institutional responsibilities

Representative of PhD students within the Board of the Department (DeFENS) of the University of Milan.